Sensor for determining concentration of gas

• US 9,636,058 B2
• Filed: 02/19/2013
• Issued: 05/02/2017
• Est. Priority Date: 03/01/2012
• Status: Active Grant

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.), Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Van Kesteren, Hans Willem, Kahlman, Josephus Arnoldus Henricus Maria, Lambert, Nicolaas
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Liu, Chu Chuan (JJ)
• Application Number:
  US14/380,852
• Publication Number:
  US 20150011852A1
• Time in Patent Office: 1,533 Days
• Field of Search: 600309, 600310, 600311, 600312, 600322, 600323, 600326, 600329, 600333, 600340
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/14556 by fluorescence A61B5/14555 takes precedence
• CPC Class Codes: A61B 5/1491 Heated applicators
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/202 partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)
• CPC Class Codes: G01N 21/17 Systems in which incident light is modified in accordance with the properties of the material investigated where the material investigated is optically excited causing a change in wavelength of the incident light G01N21/63

Abstract

An optical sensor unit (10) for measuring a concentration of a gas is provided, comprising at least one sensing layer (122) adapted to be irradiated with a predetermined radiation; at least one gas-permeable layer (121) adjacent to one side of the at least one sensing layer (122) and adapted to pass gas which concentration is to be measured through the gas-permeable layer (121) towards the sensing layer (122); a removable protective layer (150) covering at least the gas-permeable layer (121) and adapted to be removed before use of the optical sensor unit (10), wherein the optical sensor unit (10) is adapted to measure an optical response of the at least one sensing layer (122), which optical response depends on the concentration of the gas.

Claims

1. Optical sensor unit for measuring a concentration of a gas, comprising:

a first gas-permeable layer adjacent to a first side of at least one sensing layer and adapted to pass gas which concentration is to be measured through the first gas-permeable layer towards the at least one sensing layer;

the at least one sensing layer adapted to be irradiated with a predetermined radiation and to emit a corresponding optical response, wherein the optical response depends on the concentration of the gas;

a fluid film or a contact medium interposed between the first gas-permeable layer and a second gas-permeable layer, the fluid film or the contact medium being on a side of the first gas-permeable layer that is opposite the at least one sensing layer,

a removable protective layer covering at least the second gas-permeable layer and adapted to be removed before use of the optical sensor unit;

an adhesive layer interposed between the removable protective layer and a structure supporting at least the at least one sensing layer and/or the first gas-permeable layer; and

the second gas-permeable layer interposed between the removable protective layer and the fluid film or the contact medium, wherein the first gas-permeable layer and the second gas-permeable layer confine at least part of the fluid film or the contact medium there-between.

2. Optical sensor unit of claim 1, wherein it is the contact medium that is interposed between the first gas-permeable layer and the second gas-permeable layer, the contact medium being a gel or a liquid, wherein the contact medium is adapted to control the water content of the first gas-permeable layer and/or the at least one sensing layer.

3. Optical sensor unit according to claim 1, further comprising an optically transparent layer adjacent to a second side of the at least one sensing layer and adapted to cover and protect the at least one sensing layer from direct contact with a surrounding atmosphere.

4. Optical sensor unit according to claim 1, further comprising a structure adjacent to the first gas-permeable layer and having cavities, wherein it is the contact medium that is interposed between the first gas-permeable layer and the second gas-permeable layer, and wherein the contact medium is arranged in the cavities.

5. Optical sensor unit according to claim 1, wherein the adhesive layer is attached to an object interchanging gas after removal of the protective layer.

6. Optical sensor unit according to claim 1, wherein the adhesive layer comprises a first adhesive layer, a second adhesive layer and a support layer interposed between the first adhesive layer and the second adhesive layer.

7. Optical sensor unit according to claim 6,

wherein it is the contact medium that is interposed between the first gas-permeable layer and the second gas-permeable layer, and

wherein the first adhesive layer has at least one opening for exposing the first gas-permeable layer and/or the contact medium, the second adhesive layer and the support layer covering the first gas-permeable layer and/or the contact medium and being perforated in a portion thereof corresponding to the first gas-permeable layer.

8. Optical sensor unit according to claim 1, wherein the at least one sensing layer comprises a luminescent material.

9. Optical sensor unit according to claim 1, wherein the first gas-permeable layer is adapted to prevent light from passing through the first gas-permeable layer.

10. Optical sensor unit according to claim 1, wherein the removable protective layer comprises plastic and/or metal and/or is optically opaque and/or is gas-impermeable.

11. Optical sensor unit according to claim 1, wherein the optical sensor unit is a transcutaneous sensor unit for measuring blood gas concentrations, in particular gas concentrations of O₂ and/or CO₂.

12. Optical sensor unit according to claim 1, further comprising:

at least one light source or at least one light guiding structure adapted to irradiate the sensing layer with light;

the at least one light guiding structure or a detection device adapted to detect the optical response of the sensing layer, wherein at least one of the light source, light guiding structure and/or the detection device are detachably connected to the optical sensor unit.

13. System for patient monitoring and/or ventilation of a patient, comprising an optical sensor unit according to claim 1, a ventilation device and a monitoring device.

14. Optical sensor unit according to claim 1, further comprising:

a heating element provided at a lateral side of the at least one sensing layer and the first gas-permeable layer for heating skin of a patient to increase blood perfusion and gas permeability of the skin.

15. Optical sensor unit according to claim 14, wherein the heating element comprises a compartment for providing a reservoir that connects to the fluid film or the contact medium.

16. Optical sensor unit according to claim 1, wherein one or more of the at least one sensing layer, the first gas-permeable layer, and the removable protective layer are packaged in an air and light tight package during storage.

17. A method for measuring a concentration of gas using an optical sensor unit comprising a first gas-permeable layer adjacent to one side of at least one sensing layer and adapted to pass gas which concentration is to be measured through the first gas-permeable layer towards the at least one sensing layer, the at least one sensing layer adapted to be irradiated with a predetermined radiation and to emit a corresponding optical response, the optical response depending on the concentration of the gas, a fluid film or a contact medium interposed and confined between a side of the first gas-permeable layer that is opposite the at least one sensing layer and a second gas-permeable layer, the fluid film or the contact medium being a gel, fluid, buffer solution, or a liquid, the second gas-permeable layer interposed between a removable protective layer and the fluid film or the contact medium, an adhesive layer interposed between the removable protective layer and a structure supporting at least the at least one sensing layer and/or the first gas-permeable layer, and the removable protective layer covering at least the second gas-permeable layer and adapted to be removed before use of the optical sensor unit, wherein the fluid film or the contact medium is adapted to control the water content of the first gas-permeable layer and/or the at least one sensing layer, the method comprising the steps of:

removing the protective layer from the optical sensor unit,

attaching the optical sensor unit to an object releasing gas using the adhesive layer,

receiving gas which concentration is to be measured in the at least one sensing layer after passing the first gas-permeable layer,

irradiating the at least one sensing layer with the predetermined radiation, and

sensing the optical response of the at least one sensing layer, which depends on the concentration of the gas.

18. The method according to claim 17, wherein the optical sensor unit further comprises a heating element provided at a lateral side of the at least one sensing layer and the first gas-permeable layer for heating skin of a patient to increase blood perfusion and gas permeability of the skin.

19. The method according to claim 18, wherein the heating element comprises a compartment for providing a reservoir that connects to the fluid film or the contact medium.