Method and apparatus for automatic cancer diagnosis scoring of tissue samples

  • US 9,652,844 B2
  • Filed: 03/18/2015
  • Issued: 05/16/2017
  • Est. Priority Date: 07/13/2012
  • Status: Active Grant
First Claim
Patent Images

1. A non-transitory computer-readable storage medium storing one or more computer programs adapted to cause a processor based system to execute steps comprising:

  • converting at least a part of image information of a tissue sample to an optical domain image;

    separating the at least a part of image information into positive stain image information and negative stain image information;

    identifying a number of positive stained nuclei based on the positive stain image information and a number of negative stained nuclei based on the negative stain image information;

    calculating a number of total nuclei by summing the number of positive stained nuclei and the number of negative stained nuclei, wherein a percentage score is calculated based on the number of positive stained nuclei and the number of total nuclei; and

    displaying an indication of a cancer diagnosis score derived at least in part from the percentage score.

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