Method and apparatus for monitoring the condition of a patient with diabetes

• US 9,662,462 B2
• Filed: 01/30/2014
• Issued: 05/30/2017
• Est. Priority Date: 02/17/2006
• Status: Active Grant

• Current Assignee: ResMed Pty Ltd. (ResMed Incorporated)
• Original Assignee: Resmed Limited (ResMed Incorporated)
• Inventors: Darkin, Donald, Schindhelm, Klaus Henry, Harrington, Carmel Therese
• Primary Examiner(s): Dixon, Annette
• Application Number:
  US14/168,860
• Publication Number:
  US 20140144431A1
• Time in Patent Office: 1,216 Days
• Field of Search: 12820024, 12820123, 12820216, 12820222, 12820418, 12820421, 12820422, 12820423, 12820424, 12820426, 12820523, 12820525, 12820621, 12820624, 12820626, 12820628, 12820714, 128857, 128863, 128905, 128921, 600300, 600309, 600323, 600345, 600347, 600365, 600383, 600390, 600393, 600479, 600484, 600529, 600531, 600532, 600538, 600544, 600546, 600547, 600549, 600586
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/0531 Measuring skin impedance
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/372 Analysis of electroencephalograms
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/0683 Holding devices therefor
• CPC Class Codes: A61M 2016/0036 in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3584 using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2230/06 Heartbeat rate only
• CPC Class Codes: A61M 2230/10 : Electroencephalographic signals
• CPC Class Codes: A61M 2230/201 : Glucose concentration
• CPC Class Codes: A61M 2230/42 : Rate
• CPC Class Codes: A61M 2230/50 : Temperature
• CPC Class Codes: A61M 2230/65 : Impedance, e.g. conductivity, capacity

Abstract

An apparatus for treatment of a patient with both sleep-disordered breathing and diabetes includes: a blower configured to provide a supply of air at positive pressure; a patient interface; headgear to hold the patient interface in position in communication with a patient'"'"'s airways; at least one hypoglycemia sensor; an alarm; and a controller, wherein the controller is programmed to receive a signal from the at least one hypoglycemia detector, analyze the signal for indications of hypoglycemia and upon detection of an indication of hypoglycemia trigger the alarm.

Claims

1. An apparatus for treatment of a patient with both sleep-disordered breathing and diabetes, comprising:

a flow generator configured to provide a supply of air at positive pressure;

a patient interface;

at least one glycemia abnormality detector attached to the patient interface and including a sensor configured for communication with mucosal regions of the patient'"'"'s nares;

headgear adapted to hold the patient interface in position in communication with a patient'"'"'s airways and thereby hold the sensor in position for communication with mucosal regions of the patient'"'"'s nares throughout the treatment;

an alarm; and

a controller,

wherein the controller is programmed to receive a signal from the at least one glycemia abnormality detector, analyze the signal for indications of glycemia abnormality and, upon detection of an indication of glycemia abnormality, trigger the alarm.

2. The apparatus according to claim 1, wherein said at least one glycemia abnormality detector is further configured to detect activation of the sympathetic nervous system.

3. The apparatus according to claim 1, wherein said at least one glycemia abnormality detector is further configured to detect at least one of:

patient sweating, temperature, heart rate, and respiration rate.

4. The apparatus according to claim 1, further comprising a flow sensor in fluid communication with the patient interface.

5. The apparatus according to claim 1, wherein said alarm is local to the patient interface.

6. The apparatus according to claim 1, wherein said alarm is sent to a remote monitoring system.

7. The apparatus according to claim 1, wherein the alarm is operable to sound an audible alert when the signal indicates the glycemia abnormality.

8. The apparatus according to claim 1, wherein the controller is configured to transmit information to a remote location when the signal indicates one or more of:

hypoglycemia, hyperglycemia, and diabetic coma.

9. The apparatus according to claim 1, further comprising a drug delivery unit.

10. The apparatus according to claim 1, wherein the drug delivery unit is configured to supply at least one of glucose and insulin to the patient.

11. A method of treating a patient with both sleep-disordered breathing and diabetes, the method comprising:

providing a supply of pressurized breathable gas to the patient through a patient interface using a PAP device;

providing at least one glycemia abnormality detector attached to the patient interface and including a sensor configured for communication with mucosal regions of the patient'"'"'s nares;

providing headgear adapted to hold the patient interface in position for communication with a patient'"'"'s airways, thereby holding the sensor in position for communication with mucosal regions of the patient'"'"'s nares for throughout treatment of the patient; and

generating a signal indicative of whether the patient is experiencing a diabetic event, the signal being based on data gathered from (a) the sensor in communication with mucosal regions of the patient'"'"'s nares, and (b) a second sensor built into headgear that is adapted to hold the patient interface in a position suitable for communicating the supply of pressurized breathable gas to the patient'"'"'s airways.

12. The method according to claim 11, further comprising when the signal indicates that the patient is experiencing a diabetic event, activating an alert mechanism.

13. The method according to claim 12, wherein the activating of the alert mechanism is further practiced by sounding an audible alarm.

14. The method according to claim 12, wherein the activating of the alert mechanism is further practiced by notifying a remote monitoring station.

15. The method according to claim 11, further comprising when the signal indicates that the patient is experiencing a diabetic event, administering a corresponding treatment.

16. An apparatus for treatment of a patient with both sleep-disordered breathing and diabetes, comprising:

a PAP device configured to provide a supply of pressurized breathable gas for sleep-disordered breathing treatment;

a patient interface;

at least one glycemia detector attached to the patient interface, wherein the at least one glycemia detector includes a sensor configured for contact with mucosal regions of the patient;

headgear adapted to hold the patient interface in position for communication with a patient'"'"'s airways and thereby hold the sensor in position for communication with mucosal regions of the patient'"'"'s nares throughout the treatment;

an action unit including a drug delivery unit for use in treating the patient'"'"'s diabetes; and

a controller integrated into the PAP device and operable to receive a signal from the at least one glycemia detector, analyze the signal for an indication of a glycemia abnormality, and instruct the drug delivery unit to provide a treatment to the patient for the glycemia abnormality while also instructing the PAP device to provide the supply of pressurized breathable gas.

17. The apparatus according to claim 16, wherein the drug delivery unit is configured to provide at least one of oral insulin and glucose to the patient upon receiving instructions from the controller.

18. The apparatus according to claim 16, wherein the drug delivery unit is configured to provide the treatment to the patient for the glycemia abnormality in at least one of vapor form and through aerosol delivery.

19. The apparatus according to claim 16, wherein the drug delivery unit is configured to provide at least one of insulin and glucose to the patient in at least one of vapor form and through aerosol delivery upon receiving instructions from the controller.

20. The apparatus according to claim 16, wherein said glycemia detector is further configured to detect activation of the sympathetic nervous system.