Temporary suspension for closed-loop medicament therapy

• US 9,669,160 B2
• Filed: 07/30/2015
• Issued: 06/06/2017
• Est. Priority Date: 07/30/2014
• Status: Active Grant

• Current Assignee: Tandem Diabetes Care Incorporated
• Original Assignee: Tandem Diabetes Care Incorporated
• Inventors: Harris, Paul, Berger, David
• Primary Examiner(s): Mehta, Bhisma
• Assistant Examiner(s): SHAH, NILAY J
• Application Number:
  US14/813,699
• Publication Number:
  US 20160030669A1
• Time in Patent Office: 677 Days
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

A portable infusion pump can communicate with continuous glucose monitor (CGM) to receive continuous feedback relating to a user'"'"'s blood glucose level during insulin or other medicament therapy and can automatically deliver insulin to a user when the CGM data indicates a need for additional insulin. Because patient behavior can interfere with the accuracy and efficacy of such closed loop or semi-closed loop therapy, a system can employ various mechanisms for manual temporary suspension of closed-loop therapy when a patient is aware that current or future behavior may inhibit therapy.

Claims

1. An infusion pump system, comprising:

a delivery mechanism adapted to facilitate delivery of medicament to a patient;

memory adapted to store parameters relating to the delivery of medicament;

a communications device adapted to receive information from a continuous glucose monitor; and

a processor functionally linked to the delivery mechanism and the memory and to the communications device to obtain the information from the continuous glucose monitor, the processor configured to;

cause the delivery mechanism to deliver medicament to the patient according to therapy parameters determined based on the information from the continuous glucose monitor;

determine from user-defined input that the patient is going to take or has taken a medication;

suspend delivery of medicament according to the determined therapy parameters for a suspension period in response to the determination that the patient is going to take or has taken a medication;

cause the delivery mechanism to deliver medicament according to a default medicament delivery schedule stored in memory during the suspension period; and

resume causing the delivery mechanism to deliver medicament to the patient according to the determined therapy parameters following the suspension period, and

wherein the processor is further configured to receive a duration for the suspension period entered through a user interface in communication with the processor.

2. The portable infusion pump of claim 1, wherein the processor is further configured to receive an indication of a type of medication the patient is going to take or has taken.

3. The portable infusion pump of claim 2, wherein the processor is further configured to determine whether the type of medication is one likely to cause the information from the continuous glucose monitor to become unreliable, and suspend delivery of the medicament only if the type of medication is one likely to cause the information from the continuous glucose monitor to become unreliable.

4. The portable infusion pump of claim 1, wherein the processor is configured to resume causing the delivery mechanism to deliver medicament to the patient according to the determined therapy parameters automatically following the suspension period.

5. The portable infusion pump of claim 1, wherein the processor is further configured to provide a prompt on the user interface in communication with the processor that the suspension period has ended and to resume causing the delivery mechanism to deliver the medicament to the patient according to the determined therapy parameters following the suspension period only after receiving a confirmation in response to the prompt.

6. The portable infusion pump of claim 1, wherein the processor is configured to determine the therapy parameters based on the information from the continuous glucose monitor.

7. An infusion pump system, comprising:

a delivery mechanism adapted to facilitate a delivery of a medicament to a patient;

a memory adapted to store parameters relating to the delivery of the medicament;

a communications device adapted to receive information from a continuous glucose monitor; and

a processor functionally linked to the delivery mechanism and the memory and to the communications device to obtain the information from the continuous glucose monitor, the processor configured to;

cause the delivery mechanism to deliver the medicament to the patient according to therapy parameters determined based on the information from the continuous glucose monitor;

determine from user-defined input that the patient is going to take or has taken a medication;

suspend delivery of the medicament according to the determined therapy parameters for a suspension period in response to the determination that the patient is going to take or has taken a medication;

cause the delivery mechanism to deliver the medicament according to a default medicament delivery schedule stored in the memory during the suspension period; and

resume causing the delivery mechanism to deliver the medicament to the patient according to the determined therapy parameters following the suspension period, and

wherein the processor is further configured to receive an indication of the type of the medication the patient is going to take or has taken and determine a duration for the suspension period based on the type of the medication.

8. The portable infusion pump of claim 7, wherein the processor additionally determines the duration for the suspension period based at least in part on a dosage size of the medication.

9. The portable infusion pump of claim 7, wherein the processor is further configured to determine whether the type of the medication is on likely to cause the information from the continuous glucose monitor to become unreliable, and suspend delivery of the medicament only if the type of the medication is one likely to cause the information from the continuous glucose monitor to become unreliable.

10. The portable infusion pump of claim 7, wherein the processor is configured to resume causing the delivery mechanism to deliver the medicament to the patient according to the determined therapy parameters automatically following the suspension period.

11. The portable infusion pump of claim 7, wherein the processor is further configured to provide a prompt a user interface in communication with the processor that suspension period has ended and to resume causing the delivery mechanism to deliver the medicament to the patient according to the determined therapy parameters following the suspension period only after receiving a confirmation in response to the prompt.

12. The portable infusion pump of claim 7, wherein the processor is configured to determine the therapy parameters based on the information from the continuous glucose monitor.

13. An infusion pump system, comprising:

a delivery mechanism adapted to facilitate a delivery of a medicament to a patient;

a memory adapted to store parameters relating to the delivery of the medicament;

a communications device adapted to receive information from a continuous glucose monitor; and

a processor functionally linked to the delivery mechanism and the memory and to the communications device to obtain the information from the continuous glucose monitor, the processor configured to;

cause the delivery mechanism to deliver the medicament to the patient according to therapy parameters determined based on the information from the continuous glucose monitor;

receive an indication that the patient is going to take or has taken a medication;

suspend delivery of the medicament according to the determined therapy parameters for a suspension period in response to the indication;

cause the delivery mechanism to deliver the medicament according to a default medicament delivery schedule stored in the memory during the suspension period; and

resume causing the delivery mechanism to deliver the medicament to the patient according to the determine therapy parameters following the suspension period,

wherein the processor is further configured to receive an indication of a type of medication the patient is going to take or has taken, and

wherein the processor is further configured to determine whether the type of medication is one likely to cause the information from the continuous glucose monitor to become unreliable, and suspend delivery of the medicament only if the type of medication is one likely to cause the information from the continuous glucose monitor to become unreliable.

14. The portable infusion pump of claim 13, wherein the processor is further configured to receive a duration for the suspension period entered through a user interface in communication with the processor.

15. The portable infusion pump of claim 13, wherein the processor is further configured to determine a duration for the suspension period based on the type of medication.

16. The portable infusion pump of claim 15, wherein, the processor additionally determines the duration for the suspension period based at least in part on a dosage size of the medication.

17. The portable infusion pump of claim 13, wherein the processor is configured to resume causing the delivery mechanism to deliver the medicament to the patient according to the determined therapy parameters automatically following the suspension period.

18. The portable infusion pump of claim 13, wherein the processor is further configured to provide a prompt on a user interface in communication with the processor that the suspension period has ended and to resume causing the delivery mechanism to deliver the medicament to the patient according to the determined therapy parameters following the suspension period only after receiving a confirmation in the response to the prompt.

19. The portable infusion pump of claim 13, wherein the processor is configured to determine the therapy parameters based on the information from the continuous glucose monitor.