Methods and devices for intra-atrial shunts having adjustable sizes

• US 9,757,107 B2
• Filed: 02/02/2015
• Issued: 09/12/2017
• Est. Priority Date: 09/04/2009
• Status: Active Grant

• Current Assignee: Corvia Medical, Inc.
• Original Assignee: Corvia Medical, Inc.
• Inventors: McNamara, Edward I., Sutherland, Michael W., Finch, Matthew J., Forcucci, Stephen J., Mitzel, John, Celermajer, David S., Sugimoto, Hiroatsu
• Primary Examiner(s): Zalukaeva, Tatyana
• Assistant Examiner(s): KLEIN, BENJAMIN JACOB
• Application Number:
  US14/612,022
• Publication Number:
  US 20150148731A1
• Time in Patent Office: 953 Days
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00584 Clips
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/00623 Introducing or retrieving devices therefor
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching

Abstract

Devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart of a mammal are disclosed. Devices may include an adjustable hydraulic diameter shunt portion which can be manually adjusted in vivo. Methods are provided for adjusting the flow rate of the devices in vivo.

Claims

1. An expandable device adapted for percutaneous delivery into a membrane of a patient'"'"'s heart, the device comprising:

first and second anchors adapted to contact, respectively, first and second surfaces of the membrane; and

a stent having a longitudinal axis and being connected to the first and second anchors, the stent comprising an outer cylindrical body comprising a superelastic material and a stent-like inner cylindrical body comprising a plastically deformable material and disposed within and connected to the outer cylindrical body, the stent being adapted to permit blood to flow across the membrane at a first rate;

wherein the stent-like inner cylindrical body comprises a first diameter and a second diameter which is expanded from the first diameter, wherein the stent-like inner cylindrical body will naturally remain in the expanded second diameter and permit blood to flow across the membrane at a second rate that is different from the first rate.

2. The device of claim 1, wherein the stent further comprises a cylindrical liner disposed within and attached to the inner cylindrical body.

3. The device of claim 1, wherein the outer cylindrical body has hooks and the hooks connect the outer cylindrical body to the inner cylindrical body.

4. The device of claim 1, wherein the plastically deformable material is stainless steel.

5. The device of claim 1, wherein the superelastic material is nitinol.

6. The device of claim 1 wherein each of the first and second anchors comprises a plurality of segments.

7. The device of claim 1 wherein the first anchor, the second anchor, and the stent are integrally connected.