Mass produced, low cost, portable test kit for the detection and identification of narcotics

• US 9,759,733 B1
• Filed: 04/08/2016
• Issued: 09/12/2017
• Est. Priority Date: 04/08/2016
• Status: Active Grant

• Current Assignee: S2 Detection {Nevada}, Inc.
• Original Assignee: Michael D. Callahan
• Inventors: Callahan, Michael D.
• Primary Examiner(s): Soderquist, Arlen
• Application Number:
  US15/094,825
• Time in Patent Office: 522 Days
• Field of Search: 422400, 422411, 422418, 422425, 422430, 436 92
• CPC Class Codes: G01N 2001/028 Sampling from a surface, swabbing, vaporising
• CPC Class Codes: G01N 2021/7759 Dipstick; Test strip
• CPC Class Codes: G01N 21/78 producing a change of colour
• CPC Class Codes: G01N 21/8483 Investigating reagent band test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04
• CPC Class Codes: G01N 33/946 CNS-stimulants, e.g. cocaine, amphetamines
• CPC Class Codes: G01N 33/948 Sedatives, e.g. cannabinoids, barbiturates opiates G01N33/9486
• CPC Class Codes: G01N 33/9486 Analgesics, e.g. opiates, aspirine

Abstract

A highly portable, paper and swab-based detection kit is provided for identifying Amphetamine, Cannabis, Cocaine, Heroin, selected synthetic Cannabinoid, and amphetamine based Cathinone type stimulants, and cannabis consumable products. A method of mass manufacture providing low cost kits with long term commercial shelf life and a method of use are also provided.

Claims

1. A portable detection kit for identifying the presence of a target narcotic, comprising:

a homogenous suspension of a dry chemical powder reagent mixed with an inert liquid encapsulating polymer, deposited and dried onto a solid support article, wherein the dry coated chemical powder reagent is encapsulated and thereby protected by the inert liquid polymer;

a swab device pre-wetted with a solvent to facilitate the collection and transfer of a suspected residue to the reagent coated solid support article and upon contacting the narcotic residue with the reagent coated solid support article and mixing all components together on the solid support article, a known visual colorimetric indication is produced identifying a class of an unknown target narcotic present in the suspect residue; and

a light, air, and moisture proof package into which the reagent coated solid support article and the swab device are individual hermetically sealed prior to use.

2. The portable detection kit as in claim 1, wherein the target narcotic is selected from the group consisting of Amphetamine, Cannabis, Cocaine, Heroin, selected synthetic Cannabinoid and amphetamine based Cathinone type stimulants, and cannabis consumable products.

3. The portable detection kit as in claim 1, wherein the chemical reagent comprises a dry micronized powder comprising an organic or inorganic salt of polyvalent ions or an organic dye salt, which undergo characteristic color change when combined with the target narcotic.

4. The portable detection kit as in claim 3, wherein the organic and inorganic salts of polyvalent ions are selected from the group consisting of cobalt thiocyanate, ammonium vanadate, molybdic acid, sodium molybdate, ammonium molybdate, copper sulphate, dimethylamino benzaldehyde, gallic acid, and vanillin, dimethylamino cinnamaldehyde for detection of an Amphetamine and Cannabis type stimulants.

5. The portable detection kit as in claim 3, wherein the organic dye salts are selected from the group consisting of diazonium, azo, triarylmethane, nitro, nitroso, fluorone, xanthene, quinone-imine, ketonamine, acridine, pyronin, phthalocyanine, anthraquinone, diarylmethane, thiazin, oxazin, safranin, eurhodin, rhodamine, thiazole, aminoketone, indigoid, natural, azin, tetrazolium, and indophenol classes of dyes for detection of an Amphetamine type stimulant.

6. The portable detection kit as in claim 3, wherein the organic dye salts are selected from the group consisting of 2,5-Dimethoxy-4-([4-nitrophenyl]azo)benzenediazonium chloride hemi(zinc chloride) salt, 2-Methoxy-5-methyl-4-[(4-methyl-2-nitrophenyl)azo]benzenediazonium tetrachlorozincate, 2-Methoxy-4-nitrobenzenediazonium chloride hemi(zinc chloride) salt, 3,3′

-dimethoxy[1,1′

-biphenyl]-4,4′

-bis(diazonium) dichloride, 4-benzamido-2,5-diethoxybenzene-diazonium salt zinc chloride, 4-m-Tolylazo-m-toluidine, disodium;

2-[[4-[ethyl-[(3-sulfonatophenyl)methyl]amino]phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]cyclohexa-2,5-dien-1-ylidene]methyl]benzenesulfonate, sodium;

4-[(2E)-2-(2-oxonaphthalen-1-ylidene)hydrazinyl]naphthalene-1-sulfonate, 4-benzamido-2,5-dimethoxybenzenediazonium, 2-methyl-4-[(2-methylphenyl)diazenyl]aniline;

hydrochloride, 4-methoxy-2-nitroaniline, (1Z)-1-[(4-methyl-2-nitrophenyl)hydrazinylidene]naphthalen-2-one, disodium;

(6Z)-4-amino-3-[(4-nitrophenyl)diazenyl]-5-oxo-6-(phenylhydrazinylidene)naphthalene-2,7-disulfonate, sodium;

(6Z)-4-amino-3-[[4[4-[(2,4-diaminophenyl)diazenyl]phenyl]phenyl]diazenyl]-5-oxo-6-(phenylhydrazinylidene)naphthalene-2,7-disulfonic acid, disodium;

8-(4-methylanilino)-5-[[4-[(3-sulfonatophenyl)diazenyl]naphthalen-1-yl]diazenyl]naphthalene-1-sulfonate, VB 4-N-(4-methoxyphenyl)benzene-1,4-diamine;

sulfuric acid, sodium;

4-[[4-(diethylamino)phenyl]-(4-diethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]benzene-1,3-disulfonate, 1,2,5,8-tetrahydroxyanthracene-9,10-dione, 2-[(2-chloro-4-nitrophenyl)diazenyl]-5-methoxy-4-methylaniline, 4-(4-aminophenyl)aniline, sodium;

(4E)-4-[(2-hydroxynaphthalen-1-yl)hydrazinylidene]-3-oxonaphthalene-1-sulfonate, pyranthrene-8,16-dione, trisodium;

4-[(4-anilino-5-sulfonatonaphthalen-1-yl)diazenyl]-5-hydroxynaphthalene-2,7-disulfonate, disodium;

(8Z)-7-oxo-8-(phenylhydrazinylidene)naphthalene-1,3-disulfonate, O-Nitroaniline, 3-Amino-4-chlorobenzotrifluoride, 3-amino-N-butyl-4-methoxybenzenesulfonamide, 1-aminoanthracene-9,10-dione, 5-Chloro-2-(4-chlorophenoxy)aniline, 2,5-dichloroaniline, 4-methyl-2-nitroaniline, 4-chloro-2-nitroaniline, 2-carbamoyl-5-methoxybenzenediazonium;

chloride, 3-amino-N, N-diethyl-4-methoxybenzenesulfonamide, 5-chloro-2-methoxyaniline;

hydrochloride, 2-methyl-4-nitroaniline, (1Z)-1-[[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]hydrazinylidene]naphthalen-2-one, 4-benzamido-5-chloro-2-methylbenzenediazonium;

chloride, 2,5-dichloroaniline, (1Z)-1-[(4-methyl-2-nitrophenyl)hydrazinylidene]naphthalen-2-one, sodium;

4-hydroxy-3-[(2E)-2-(2-oxonaphthalen-1-ylidene)hydrazinyl]benzenesulfonate, 2-chloroaniline, 4-diazo-2-chlorobenzene, 4-diazo-diphenylamine, diazotised N, N-diethyl-3-toluidine, diazotised 2-chloro-N, and N-diethylaniline for detection of an Amphetamine type stimulant.

7. The portable detection kit as in claim 3, wherein the characteristic color change proceeds regardless of the presence of a catalytic dry powdered alkaline organic or inorganic salt.

8. The portable detection kit as in claim 3, wherein the liquid encapsulating polymer is selected from the group consisting of acrylic emulsions, polyvinyl alcohol, polyvinyl pyrrolidone, glycol-ethers, styrene, polyester, polybutadiene, alginate, guar, polyethylene, urea, natural gums, polyether and polyamide units, styrene acrylic copolymer emulsion, Isophthalic alkyd, Nitrocellulose, Cellulose Acetate Propionate (CAP), Vinyl chloride acetate co-polymer, Polyamide, and hexamethoxymethyl melamine resin.

9. The portable detection kit as in claim 3, wherein the organic and inorganic salts of polyvalent ions are selected from the group consisting of thiocyanates, vanadates, molybdates, sulphates, citrates, tartrates, carbonates and nitrates for detection of a Heroin type stimulant.

10. The portable detection kit as in claim 9, wherein the polyvalent ions are selected from the group consisting of Cerium, Lead, Palladium, Bismuth, Tin, Iron, Cobalt, Nickel, Copper, Aluminum, Manganese, Magnesium, and Ammonium for detection of a Heroin type stimulant.

11. The portable detection kit as in claim 9, wherein the characteristic color change proceeds regardless of the presence of a catalytic dry powdered alkaline organic or inorganic salt.

12. The portable detection kit as in claim 11, wherein the catalytic dry powdered alkaline salt is selected from the group consisting of sodium carbonate, trisodium citrate, sodium hydrogen carbonate, calcium carbonate, sodium and ammonium hydroxide.

13. The portable detection kit as in claim 9, wherein the liquid encapsulating polymer is selected from the group consisting of acrylic emulsions, polyvinyl alcohol, polyvinyl pyrrolidone, glycol-ethers, styrene, polyester, polybutadiene, alginate, guar, polyethylene, urea, natural gums, polyether and polyamide units, styrene acrylic copolymer emulsion, Isophthalic alkyd, Nitrocellulose, Cellulose Acetate Propionate (CAP), Vinyl chloride acetate co-polymer, Polyamide, and hexamethoxymethyl melamine resin.

14. The portable detection kit as in claim 3, wherein the organic and inorganic salts of polyvalent ions are selected from the group consisting of thiocyanates, vanadates, molybdates, sulphates, citrates, tartrates, carbonates and nitrates for detection of a Cocaine type stimulant.

15. The portable detection kit as in claim 14, wherein the polyvalent ion is selected from the group consisting of Cerium, Lead, Palladium, Bismuth, Tin, Iron, Cobalt, Nickel, Copper, Aluminum, Manganese, Magnesium, and Ammonium.

16. The portable detection kit as in claim 3, wherein the inert liquid encapsulating polymer is selected from the group consisting of polyols, water, carbohydrates, and acids.

17. The portable detection kit as in claim 16, wherein:

the polyols comprise glycerol;

the carbohydrates are selected from the group consisting of mannitol, sucrose, fructose, hexose, and starches; and

the acids are selected from the group consisting of sodium hydrogen sulphate, citric acid, tartaric acid, and ascorbic acid.

18. The portable detection kit as in claim 1, wherein the powdered reagent comprises a plurality of powdered reagents separated from one another throughout all kit production steps.

19. The portable detection kit as in claim 1, wherein the powdered reagent comprises a plurality of powdered reagents mixed together into an homogenous powdered reagent mix.

20. The portable detection kit as in claim 19, wherein, the mixture of the plurality of reagent powders and the inert liquid encapsulating polymer comprises a stable, low viscosity, homogenized suspension.

21. The portable detection kit as in claim 1, wherein the inert liquid encapsulating polymer comprises an aqueous liquid encapsulating polymer.

22. The portable detection kit as in claim 1, wherein the inert liquid encapsulating polymer comprises a non-aqueous liquid encapsulating polymer.

23. The portable detection kit as in claim 1, wherein the dry reagent coated solid support article is formed into a strip.

24. The portable detection kit as in claim 1, wherein the solid support article is selected from the group consisting of glass, metal, paper, textiles, organic membranes, inorganic membranes, natural fibers, and synthetic fibers.

25. The portable detection kit as in claim 1, wherein the swab device comprises:

a handle; and

an absorbent matrix collection tip for surface sample collection and physical mixing of the suspect residue and the chemical reagent.

26. The portable detection kit as in claim 25, wherein the swab tip comprises absorbent synthetic or natural fibers.

27. The portable detection kit as in claim 25, wherein the swab tip comprises a dry tip.

28. The portable detection kit as in claim 25, wherein the swab tip comprises a tip pre-wetted with a solvent.

29. The portable detection kit as in claim 28, wherein the pre-wetted solvent comprises an aqueous solvent or an organic solvent.

30. The portable detection kit as in claim 29, wherein the organic solvent is selected from the group consisting of alcohols, acetone, chlorinated hydrocarbons, dimethyl sulfoxide, and organic acids.

31. The portable detection kit as in claim 29, wherein the aqueous solvent is selected from the group consisting of water, mineral acids and alkali.

32. The portable detection kit as in claim 1, wherein the package comprises a layer of a PET or cellulosic material, a layer of aluminum, and a layer of a Poly Ethylene material.

33. The portable detection kit as in claim 32, wherein:

the layer of a PET or cellulosic material is approximately 12 microns thick;

the layer of aluminum is approximately 7 microns thick; and

the layer of a Poly Ethylene material is approximately 50 microns thick.

34. A method of providing a portable detection kit for identifying the presence of a target narcotic, comprising:

mixing a homogenous suspension of a dry chemical powder reagent with an inert liquid encapsulating polymer;

depositing the encapsulated powder reagent onto a solid support article;

drying the encapsulated powder reagent;

pre-wetting a swab device with a solvent to facilitate the collection and transfer of a suspected residue to the reagent coated solid support article and upon contacting the narcotic residue with reagent coated solid support article and mixing all components together on the solid support article, a known visual colorimetric indication is produced thereby identifying a class of an unknown target narcotic present in the suspect residue; and

hermetically sealing the reagent coated solid support article and the swab device in a light, air, and moisture proof package prior to use.

35. The portable detection kit as in claim 34, wherein the target narcotic is selected from the group consisting of Amphetamine, Cannabis, Cocaine, Heroin, selected synthetic Cannabinoid and amphetamine based Cathinone type stimulants, and cannabis consumable products.

36. The method as in claim 34, further comprising mixing and homogenizing a plurality of powdered reagents in a laboratory ball, crusher, or shaker mill to produce the homogenous suspension of a dry chemical powder reagent.

37. The method as in claim 34, further comprising mixing the homogenous suspension of a dry chemical powder reagent with the inert liquid encapsulating polymer in inert mixing containers and high speed shaker beds or rotary impeller mixers.

38. The method as in claim 34, wherein depositing the encapsulated powder reagent onto the solid support article comprises an automated commercial printing process.

39. The method as in claim 38, wherein the commercial printing process is selected from the group consisting of letterpress, rotary gravure, screen printing, tampography, wax printing, contact dosing, ultrasonic sputter, and spray and drop on demand printing.

40. The method as in claim 34, wherein drying the deposited encapsulated powder reagent comprises a process selected from the group consisting of UV, IR, and hot air cure.

41. The method as in claim 34, further comprising forming the dry reagent coated solid support article into a predetermined shape by a process selected from the group consisting of injection molding, pressure forming, guillotining, and die-cutting.

42. The method as in claim 34, further comprising increasing long term chemical viability of the chemical reagent by a process selected from the group consisting of using inert liquid encapsulating suspension polymers, specific reagent mix combinations and ratios, physical separation of chemical reagents or mixtures of chemical reagents, and selective packaging.

43. The method as in claim 34, wherein depositing the encapsulated powder reagent comprises depositing a plurality of encapsulated powder reagents onto the solid support article separated by physical voids.

44. The method as in claim 34, further comprising hermetically sealing the dry reagent coated solid support article and the swab device in the package by vertical or horizontal form fill seal packaging systems.

45. The method according to claim 34, further comprising testing for the presence of a target narcotic by:

removing the dry reagent coated solid support and swab device from the sealed package;

rubbing an object with the swab device to transfer a molecule or ion of an unknown suspect residue from the object to the swab device;

contacting the swab device with the dry reagent on the solid support article to transfer the molecule or ion to the dry reagent powder; and

rubbing the swab device through the dry reagent powder on the solid support article to mix together the suspect residue, the dry reagent powder, and the swab wetting solvent;

whereby a chemical reaction is facilitated to produce a presumptive colorimetric indication of the presence of a target narcotic if a target narcotic is present.