Methods and apparatus for translating a continuous-deliver delivery profile into a plurality of periodic bolus deliveries

• US 9,770,556 B2
• Filed: 03/29/2016
• Issued: 09/26/2017
• Est. Priority Date: 12/05/2008
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medallion Therapeutics, Inc.
• Inventors: Shelton, Brian M., Minaie, Pedrum, Newbill, Jon Douglas, Lord, Peter C.
• Primary Examiner(s): Mehta, Bhisma
• Assistant Examiner(s): LEE, BRANDY SCOTT
• Application Number:
  US15/084,429
• Publication Number:
  US 20160228638A1
• Time in Patent Office: 546 Days
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2205/3355 Controlling downstream pump pressure
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2209/01 Remote controllers for specific apparatus
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16804 Flow controllers
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

Methods and apparatus for translating a continuous-delivery delivery profile into a plurality of periodic bolus deliveries.

Claims

1. A method of operating an ambulatory infusion device, comprising the steps of:

delivering, with the ambulatory infusion device, periodic boluses of an infusible substance that produce a continuous therapeutic effect;

in response to a user-initiated bolus request that occurs during a periodic bolus delivery, delivering a bolus corresponding to the user-initiated bolus request that occurs during the periodic bolus delivery at the end of the periodic bolus delivery; and

in response to a user-initiated bolus request that does not occur during a periodic bolus delivery, delivering a bolus corresponding to the user-initiated bolus request that does not occur during the periodic bolus delivery when the user-initiated bolus request that does not occur during the periodic bolus delivery is received.

2. A method as claimed in claim 1, wherein the step of delivering periodic boluses comprises delivering periodic boluses with the ambulatory infusion device as a function of a continuous-delivery delivery profile stored in the ambulatory infusion device and a bolus interval received by the ambulatory infusion device.

3. A method as claimed in claim 1, further comprising the step of:

in response to a user-initiated bolus request, and prior to the delivering the user-initiated bolus, determining whether the user-initiated bolus would, in combination with the periodic boluses delivery, create a conflict with a delivery criteria; and

in response to a conflict with a delivery criteria, preventing the delivery of the user-initiated bolus.

4. A method as claimed in claim 3, wherein

the delivery criteria comprises maximum rate per hour.

5. A method as claimed in claim 3, wherein

the delivery criteria comprises maximum single bolus dosage.

6. A method as claimed in claim 1, wherein

there are periods of non-delivery between successive boluses that produce the continuous therapeutic effect.

7. A method of operating an ambulatory infusion device, comprising the steps of:

translating a stored continuous-delivery delivery profile into a plurality of periodic boluses with periods of non-delivery between successive boluses;

delivering the periodic boluses with the ambulatory infusion device;

in response to a user-initiated bolus request that occurs during a periodic bolus delivery, delivering a bolus corresponding to the user-initiated bolus request that occurs during the periodic bolus delivery at the end of the periodic bolus delivery; and

in response to a user-initiated bolus request that does not occur during a periodic bolus delivery, delivering a bolus corresponding to the user-initiated bolus request that does not occur during the periodic bolus delivery when the user-initiated bolus request that does not occur during the periodic bolus delivery is received.