Immunogenic composition

  • US 9,789,179 B2
  • Filed: 06/23/2006
  • Issued: 10/17/2017
  • Est. Priority Date: 06/27/2005
  • Status: Active Grant
First Claim
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1. An immunogenic composition comprising Neisseria meningitidis (N. meningitidis) capsular polysaccharides from at least two of serogroups A, C, W135 and Y comprising N. meningitidis serogroup C capsular polysaccharide having an average size of above 75 kDa, conjugated to a carrier protein to produce a N. meningitidis capsular polysaccharide conjugate, and microfluidised N. meningitidis serogroup Y (MenY) capsular polysaccharide having an average size of above 120 kDa, conjugated to a carrier protein to produce a N. meningitidis capsular polysaccharide conjugate, wherein the average size of each N. meningitidis polysaccharide is above 50 kDa.

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