Ocular Videography System

• US 9,801,539 B2
• Filed: 05/23/2014
• Issued: 10/31/2017
• Est. Priority Date: 05/23/2013
• Status: Active Grant

• Current Assignee: Stiftung Caesar Center Of Advanced European Studies And Research
• Original Assignee: Stiftung Caesar Center Of Advanced European Studies And Research
• Inventors: Kerr, Jason, Wallace, Damian Haydon, Sawinski, Juergen, Greenberg, David
• Primary Examiner(s): Haque, Md
• Application Number:
  US14/286,897
• Publication Number:
  US 20150077543A1
• Time in Patent Office: 1,257 Days
• CPC Class Codes: A61B 2503/40 Animals
• CPC Class Codes: A61B 3/113 for determining or recording eye movement
• CPC Class Codes: A61B 3/145 by video means
• CPC Class Codes: H04N 23/51 Housings
• CPC Class Codes: H04N 23/56 provided with illuminating means
• CPC Class Codes: H04N 5/33 Transforming infrared radiation cameras or camera modules for generating image signals from infrared radiation H04N23/20; circuitry of SSIS for transforming infrared radiation into image signals H04N25/20

Abstract

The present invention relates to an Ocular Videography System for tracking eye movements of an animal, in particular rats, comprising a camera system suitable of being positioned on the head of an animal to track eye movements of at least one eye of the animal, a head mount on which the camera system is fixed or fixable, wherein, at least one image sensor as well as at least one decoder, for decoding a signal detected by the image sensor, each being comprised by the camera system, and wherein the camera system, and in particular a camera of the camera system, is designed in such a way that it detects a movement of the eye and/or a movement of the head of the animal in a vertical and/or horizontal and/or a torsional direction to an optical axis of the camera system and/or of the optical axis of the animal'"'"'s eye without interfering with the animal'"'"'s natural motion dynamics.

Claims

1. An ocular videography system for tracking eye movements of an animal comprising:

a) a camera system suitable for being positioned on a head of an animal to track eye movements of at least one eye of the animal, said camera system comprising at least one image sensor as well as at least one decoder for decoding a signal detected by the image sensor, wherein the at least one decoder is physically separate from the at least one image sensor;

b) a head mount on which the camera system is fixed or fixable, wherein the camera system is designed in such a way to detect movements of the eye and/or a movement of the head of the animal in a vertical direction, horizontal direction, torsional direction, or combinations thereof, relative to an optical axis of the camera system or the optical axis of the eye of the animal, or both, without interfering with natural motion dynamics of the animal; and

c) a head position tracking system designed to track a position of the head of the animal within a predefined, stationary coordinate system originating outside of the body of the animal, wherein said head position tracking system comprises three tracking arms mounted on the head mount in a predefined position to each other, wherein each of the tracking arms comprises one or more light emitting elements, and the head position tracking system further comprises a head movement detection device mounted off of the body of the animal and stationary within the coordinate system, wherein the head movement detection device is able to detect movement of the tracking arm light emitting elements and is able to calculate a position of the head of the animal within said stationary coordinate system according to position and/or movement of the tracking arm light emitting elements.

2. The ocular videography system according to claim 1, wherein the camera system is designed and mounted securely on the head mount without interfering with the animal'"'"'s field of view.

3. The ocular videography system according to claim 1, wherein the decoder for decoding the signal detected by the image sensor is mounted off of the animal.

4. The ocular videography system according to claim 1, wherein the camera system comprises at least one light emitting element for guiding and emitting light towards the eye of the animal, at least one light reflector for reflecting at least partially the light reflected from the eye of the animal to the image sensor of the camera system, wherein the camera system is mounted on the head mount outside of a visual field of the eye of the animal.

5. The ocular videography system according to claim 4, wherein the camera system light emitting element is arranged within the camera system such that it illuminates the eye of the animal off-axis to the optical axis of the eye of the animal.

6. The ocular videography system according to claim 4, wherein the camera system light emitting element is a light emitting diode (LED) emitting light at least in the infrared (IR) optical spectrum, which is outside the animal'"'"'s visible spectrum.

7. The ocular videography system according to claim 6, wherein the reflector transmits at least partially light in the visible spectrum of the animal and reflects light in the infrared spectrum of light.

8. The ocular videography system according to claim 6, further comprising an IR-transmission filter as an element of the camera system, wherein said IR-transmission filter is arranged in an optical path of the light emitted by the camera system light emitting element and prevents superimposition of light in the visible optical spectrum with the light emitted by said camera system light emitting element.

9. The ocular videography system according to claim 4, wherein the camera system comprises a lens unit for guiding light at least partially emitted by the camera system light emitting element into the image sensor of the camera system.

10. The ocular videography system according to claim 9, wherein the lens unit comprises a plano-convex lens having an aperture between 0.02 mm and 1.2 mm.

11. The ocular videography system according to claim 9, wherein the lens unit is glued to a camera chip.

12. The ocular videography system according to claim 1 further comprising a core engine implemented within a processor of the camera system controlling measurement parameters of the camera system and capable of streaming data onto one or more hard drives.

13. The ocular videography system according to claim 12, wherein the core engine is capable of processing independent eye movements of both eyes of the animal.

14. An ocular videography system for tracking eye movements of an animal comprising:

a) a camera system suitable for being positioned on a head of an animal to track eye movements of at least one eye of the animal, said camera system comprising at least one image sensor as well as at least one decoder for decoding a signal detected by the image sensor, wherein the at least one decoder is physically separate from the at least one image sensor;

b) a head mount on which the camera system is fixed or fixable, wherein the camera system is designed in such a way to detect movements of the eye and/or a movement of the head of the animal in a vertical direction, horizontal direction, torsional direction, or combinations thereof, relative to an optical axis of the camera system or the optical axis of the eye of the animal, or both, without interfering with natural motion dynamics of the animal; and

c) a head position tracking system designed to track a position of the head of the animal within a predefined, stationary coordinate system originating outside of the body of the animal, wherein said head position tracking system comprises three tracking arms mounted on the head mount in a predefined position to each other, wherein each of the tracking arms comprises one or more tracking arm light emitting elements, and wherein the camera system comprises at least one camera system light emitting element for guiding and emitting light towards the eye of the animal, at least one light reflector for reflecting at least partially the light reflected from the eye of the animal to the image sensor of the camera system, wherein the camera system is mounted on the head mount outside of a visual field of the eye of the animal, and wherein the system is able to calculate a position of the head or eye of the animal within a stationary coordinate system according to position and/or movement of light received from the reflector and/or tracking arm light emitting elements.

15. The ocular videography system according to claim 14, wherein the decoder for decoding the signal detected by the image sensor is mounted off of the animal.

16. The ocular videography system according to claim 14, wherein the camera system light emitting element is arranged within the camera system such that it illuminates the eye of the animal off-axis to the optical axis of the eye of the animal.

17. The ocular videography system according to claim 14, wherein the camera system light emitting element is a light emitting diode (LED) emitting light at least in the infrared (IR) optical spectrum which is outside the animal'"'"'s visible spectrum.

18. The ocular videography system according to claim 17, further comprising an IR-transmission filter as an element of the camera system, wherein said IR-transmission filter is arranged in an optical path of the light emitted by the camera system light emitting element and prevents superimposition of light in the visible optical spectrum with the light emitted by said camera system light emitting element.

19. The ocular videography system according to claim 14, wherein the camera system comprises a lens unit for guiding light at least partially emitted by the camera system light emitting element into the image sensor of the camera system, wherein the lens unit comprises a plano-convex lens having an aperture between 0.02 mm and 1.2 mm.

20. The ocular videography system according to claim 14 further comprising a core engine implemented within a processor of the camera system controlling measurement parameters of the camera system and capable of streaming data onto one or more hard drives.