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Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin

  • US 9,821,032 B2
  • Filed: 05/09/2012
  • Issued: 11/21/2017
  • Est. Priority Date: 05/13/2011
  • Status: Active Grant
First Claim
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1. A method for improving glycemic control in a patient with type 2 diabetes mellitus comprising administering to the patient in need thereof a therapeutically effective amount of a pharmaceutical combination comprising:

  • (a) lixisenatide or a pharmaceutically acceptable salt thereof, and(b) insulin glargine or a pharmaceutically acceptable salt thereof,wherein the patient'"'"'s type 2 diabetes mellitus is inadequately controlled after treatment with basal insulin at a dose of about 15 units to about 80 units per day for at least about 3 months.

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