Blood set component connection detection

• US 9,844,620 B2
• Filed: 12/16/2013
• Issued: 12/19/2017
• Est. Priority Date: 12/20/2012
• Status: Active Grant

• Current Assignee: Gambro Lundia AB (Baxter International Inc.)
• Original Assignee: Gambro Lundia AB (Baxter International Inc.)
• Inventors: Stuva, Rickie L., Fyten, Steve, O'Mahony, John
• Primary Examiner(s): Wiest, Philip R
• Application Number:
  US14/653,008
• Publication Number:
  US 20150335809A1
• Time in Patent Office: 1,464 Days
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00 ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/267 used for pumping
• CPC Class Codes: A61M 1/3641 Pressure isolators
• CPC Class Codes: A61M 1/367 Circuit parts not covered by the preceding subgroups of group A61M1/3621
• CPC Class Codes: A61M 2205/07 having air pumping means
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: Y10T 137/0402 Cleaning, repairing, or assembling
• CPC Class Codes: Y10T 137/85986 Pumped fluid control

Abstract

Extracorporeal blood treatment systems and methods to detect the connection of one or more components (e.g., of an extracorporeal blood set) thereto (e.g., to one or more pressure transducers contained in the system housing) by, for example, controlling an air pump apparatus to provide air to a connection port at which the component is to be connected and monitoring pressure resulting therefrom to detect whether the component is operatively connected (e.g., based on a detected change in the monitored pressure due to the increased resistance, based on a monitored rate of decay of pressure of injected air, etc.).

Claims

1. An extracorporeal blood treatment system comprising:

an air pump apparatus;

one or more pressure transducers;

a controller operatively coupled to the air pump apparatus and the one or more pressure transducers;

a system housing to contain at least the air pump apparatus, the controller, and the one or more pressure transducers; and

an extracorporeal blood set comprising a plurality of components configured to be mounted on the system housing of the extracorporeal blood treatment system using connection apparatus, wherein the connection apparatus comprises one or more ports to connect the one or more pressure transducers contained in the system housing to one or more components of the plurality of components of the extracorporeal blood set when mounted on the system housing, wherein the controller is configured to;

control the air pump apparatus to provide air to at least one port of the one or more ports and within at least a portion of one or more components when mounted on the system housing using the connection apparatus; and

monitor air pressure resulting from the provision of air to the at least one port using at least one of the one or more pressure transducers to detect whether one or more components of the plurality of components are operatively connected to the system housing.

2. The system of claim 1, wherein the extracorporeal blood set comprises one or more components comprising a closed container portion mountable on the system housing of the extracorporeal blood treatment system, wherein the closed container portion is operatively connectable to at least one of the one or more pressure transducers, and further wherein the controller is configured to:

control provision of air from the air pump apparatus to at least one port of the one or more ports and within the closed container portion of at least one component when mounted on the system housing using the connection apparatus, wherein the at least one component creates an increase in resistance to the air provided when mounted on the system housing; and

monitor air pressure resulting from the provision of air to the at least one port to determine whether the component comprising the closed container portion is operatively connected to the system housing based on a detected rise in the monitored pressure due to the increased resistance.

3. The system of claim 1, wherein the extracorporeal blood set comprises a plurality of pressure measurement apparatus configured to be mounted on the system housing of the extracorporeal blood treatment system, wherein each of the plurality of pressure measurement apparatus comprises a pressure pod body configured to be mounted on the system housing and a diaphragm separating a fluid side cavity and a transducer side air cavity, wherein the transducer side air cavity is operatively connectable to at least one of the one or more pressure transducers such that pressure of fluid when present in the fluid side cavity is transferred to the transducer side air cavity via the diaphragm and measureable using the at least one pressure transducer, and further wherein the controller is configured to:

control provision of air from the air pump apparatus to at least one port of the one or more ports and into the transducer side air cavity of a first pressure measurement apparatus of the plurality of pressure measurement apparatus when mounted on the system housing; and

monitor air pressure resulting from the provision of air to the at least one port to detect whether the first measurement apparatus is operatively connected to the system housing based on a detected rise in the monitored pressure.

4. The system of claim 3, wherein the controller is configured to detect a rise in pressure by comparing the resulting air pressure to a predetermined pressure threshold and determining that the first pressure measurement apparatus is operatively connected if a predetermined number of samples thereof satisfy the predetermined pressure threshold.

5. The system of claim 3, wherein the controller is configured to detect a rise in pressure by monitoring pressure at the at least one port prior to and after providing air thereto to detect a pressure difference.

6. The system of claim 1, wherein the extracorporeal blood set comprises an open line element configured to be mounted on the system housing of the extracorporeal blood treatment system and connectable to a port of the one or more ports of the connection apparatus, wherein the open line element is operatively connected to at least one of the one or more pressure transducers when mounted on the system housing, and further wherein the controller is configured to:

control injection of air to the port of the one or more ports using the air pump apparatus and within the open line element when mounted on the system housing, wherein the open line element creates an increase in resistance to the injected air when mounted on the system housing resulting in a decreased rate of decay of the pressure of the injected air; and

monitor a rate of decay of pressure of the injected air to determine whether the open line element is operatively connected to the system housing.

7. The system of claim 6, wherein the controller is further configured to monitor the rate of decay of pressure by:

determining a pressure difference integral of the injected air over a period of time following the injection of pressurized air to the port by integrating a difference between the pressure when air is being injected to the port and an initial pressure prior to air being injected to the port;

comparing the pressure difference integral to a predetermined pressure integral threshold; and

detecting that the open line element is operatively connected if the pressure difference integral satisfies the predetermined pressure integral threshold.

9. The system of claim 1, wherein the system further comprises a clarifying air filter connected between the air pump apparatus and the one or more ports.

10. The system of claim 1, wherein the system further comprises a plurality of valves, and further wherein the controller is configured to operate a different valve for each component of the plurality of components to be mounted on the system housing to allow air from the air pump apparatus to be provided for use in detecting whether each respective component of the plurality of components to be mounted has been operatively connected.

11. The system of claim 1, wherein the plurality of components of the extracorporeal blood set comprises at least a predetermined number of pressure measurement apparatus to be operatively connected to the one or more pressure transducers, and further wherein the controller is further configured to:

detect, during a period of time, whether each of the predetermined number of pressure measurement apparatus has been operatively connected; and

alert a user if all of the predetermined number of pressure measurement apparatus have not been operatively connected during the period of time.

12. The system of claim 1, wherein the system further comprises a user interface, and wherein the controller is further configured to automatically instruct a user, via the user interface, to perform another task upon detecting that a first component of the one or more components is operatively connected.

13. The system of claim 12, wherein the controller is further configured to automatically instruct a user, via the user interface, to attach one or more additional components of the plurality of components and, respectively, detect whether each of the one or more additional components are operatively connected to the system housing upon detecting that a first component of the one or more components is operatively connected.

8. An extracorporeal blood treatment system comprising:

an air pump apparatus;

one or more pressure transducers;

a controller operatively coupled to the air pump apparatus and the one or more pressure transducers;

a system housing to contain at least the air pump apparatus, the controller, and the one or more pressure transducers; and

an extracorporeal blood set comprising a plurality of components, wherein the plurality of components comprise a plurality of pressure measurement apparatus configured to be mounted on the system housing of the extracorporeal blood treatment system, wherein each of the plurality of pressure measurement apparatus comprises a pressure pod body configured to be mounted on the system housing and a diaphragm separating a fluid side cavity and a transducer side air cavity, wherein the transducer side air cavity is operatively connectable to at least one of the one or more pressure transducers such that pressure of fluid when present in the fluid side cavity is transferred to the transducer side air cavity via the diaphragm and measureable using the at least one pressure transducer,

wherein the controller is configured to;

control the air pump apparatus to provide a positive air flow from the air pump apparatus to at least one port of the one or more ports into the transducer side air cavity of a pressure measurement apparatus of the plurality of pressure measurement apparatus when mounted on the system housing or provide a negative air flow from at least one port of the one or more ports opposite the positive air flow; and

monitor air pressure resulting from the provision of air by the air pump to detect whether the pressure measurement apparatus is operatively connected to the system housing based on a detected change in the pressure magnitude.

14. A method of connecting one or more components of an extracorporeal blood set to a housing of an extracorporeal blood treatment system, wherein the system housing contains one or more pressure transducers and an air pump apparatus, and further wherein the system comprises connection apparatus comprising one or more ports to connect the one or more pressure transducers to the one or more components of the extracorporeal blood set, wherein the method comprises:

providing an extracorporeal blood set comprising a plurality of components configured to be mounted on the system housing of the extracorporeal blood treatment system;

instructing a user, via a user interface, to connect a first component of the plurality of components;

providing air generated by the air pump apparatus to at least one of the one or more ports for use in determining whether the first component is operatively connected to the system housing via the at least one port such that a pressure associated with the first component is measureable using at least one of the one or more pressure transducers; and

automatically instructing a user, via the user interface, to perform another task upon detecting that the first component is operatively connected.

15. The method of claim 14, wherein providing the extracorporeal blood set comprises providing one or more components comprising a closed container portion mountable on the system housing of the extracorporeal blood treatment system, wherein the closed container portion is operatively connectable to at least one of the one or more pressure transducers, and further wherein providing air generated by the air pump apparatus comprises:

controlling provision of air from the air pump apparatus to at least one port of the one or more ports and within the closed container portion of at least one component when mounted on the system housing using the connection apparatus; and

monitoring air pressure resulting from the provision of air to the at least one port to determine whether the component comprising the closed container portion is operatively connected to the system housing based on a detected rise in the monitored pressure.

16. The method of claim 14, wherein providing an extracorporeal blood set comprising a plurality of components comprises providing an extracorporeal blood set comprising a plurality of pressure measurement apparatus configured to be mounted on the system housing of the extracorporeal blood treatment system, wherein each of the plurality of pressure measurement apparatus comprises a pressure pod body configured to be mounted on the system housing and a diaphragm separating a fluid side cavity and a transducer side air cavity, wherein the transducer side air cavity is operatively connectable to at least one pressure transducer of the one or more pressure transducers such that pressure of fluid when present in the fluid side cavity is transferred to the transducer side air cavity via the diaphragm and measureable using the at least one pressure transducer, and further wherein providing air generated by the air pump apparatus for use in determining whether the first component is operatively connected to the system housing comprises:

providing air from the air pump apparatus to at least one port of the one or more ports and into the transducer side air cavity of a first pressure measurement apparatus of the plurality of pressure measurement apparatus when mounted on the system housing; and

monitoring air pressure resulting from the provision of air to the at least one port to detect whether the first measurement apparatus is operatively connected to the system housing based on a detected rise in the monitored pressure.

17. The method of claim 14, wherein determining whether the first component is operatively connected to the system housing comprises detecting a rise in pressure if the first component is operatively connected to the system housing, wherein detecting a rise in pressure if the first component is operatively connected to the system housing comprises:

comparing the pressure to a predetermined pressure threshold; and

determining that the first component is operatively connected if a predetermined number of samples of the resulting air pressure satisfy the predetermined pressure threshold.

18. The method of claim 14, wherein providing an extracorporeal blood set comprises providing a predetermined number of components to be operatively connected to the system housing, and further wherein the method comprises:

detecting, during a period of time, whether each of the predetermined number of components have been operatively connected; and

alerting a user if all of the predetermined number of components have not been operatively connected during the period of time.

19. The method of claim 14, wherein providing the extracorporeal blood set comprises providing an open line element configured to be mounted on the system housing of the extracorporeal blood treatment system and connectable to a port of the one or more ports of the connection apparatus, wherein the open line element is operatively connected to at least one of the one or more pressure transducers when mounted on the system housing, and further wherein providing air generated by the air pump apparatus comprises:

controlling injection of air to the port of the one or more ports using the air pump apparatus and within the open line element when mounted on the system housing; and

monitoring a rate of decay of pressure of the injected air to determine whether the open line element is operatively connected to the system housing.

20. The method of claim 19, wherein monitoring a rate of decay of pressure of the injected air comprises:

determining a pressure difference integral of the injected air over a period of time following the injection of pressurized air to the port;

comparing the pressure difference integral to a predetermined pressure integral threshold; and

detecting that the open line element is operatively connected if the pressure difference integral satisfies the predetermined pressure integral threshold.

21. The method of claim 14, wherein automatically instructing a user, via the user interface, to perform another task comprises instructing a user, via a user interface, to attach one or more additional components of the plurality of components and, respectively, determine whether each of the one or more additional components are operatively connected.

22. The method of claim 14, wherein automatically instructing a user, via the user interface, to perform another task comprises automatically instructing a user, via the user interface, to perform another task upon detecting that the first component is operatively connected without requiring a user to confirm, via the user interface, that the first component is operatively connected.

23. The method of claim 14, wherein the method further comprises operating a different valve for each component of the plurality of components to be mounted on the system housing to allow air from the air pump apparatus to be used for determining whether each respective component of the plurality of components to be mounted has been operatively connected.

24. A method of connecting one or more pressure measurement apparatus of an extracorporeal blood set to a housing of an extracorporeal system, wherein the system housing contains one or more pressure transducers and an air pump apparatus, and further wherein the system comprises connection apparatus comprising one or more ports to connect the one or more pressure transducers to the one or more pressure measurement apparatus of the extracorporeal blood set, wherein the method comprises:

providing one or more pressure measurement apparatus of an extracorporeal blood set, wherein each of the one or more pressure measurement apparatus comprises a pressure pod body configured to be mounted on the system housing and a diaphragm separating a fluid side cavity and a transducer side air cavity, wherein the transducer side air cavity is operatively connectable to at least one pressure transducer of the one or more pressure transducers such that pressure of fluid when present in the fluid side cavity is transferred to the transducer side air cavity via the diaphragm and measureable by the at least one pressure transducer;

providing air generated by the air pump apparatus to a port of the one or more ports and into the transducer side air cavity of a first pressure measurement apparatus when mounted on the system housing; and

monitoring air pressure resulting from the provision of air to the port to detect whether the first pressure measurement apparatus is operatively connected to the system housing based on a detected rise in the monitored pressure.

25. The method of claim 24, wherein detecting a rise in the monitored pressure comprises:

comparing the pressure to a predetermined pressure threshold; and

determining that the pressure measurement apparatus is operatively connected if a predetermined number of samples of the pressure satisfy the predetermined pressure threshold.

26. The method of claim 24, wherein the method further comprises automatically instructing a user, via a user interface, to attach one or more additional pressure measurement apparatus of the one or more pressure measurement apparatus if the first pressure measurement apparatus is operatively connected, and, respectively, determine whether the one or more additional pressure measurement apparatus are operatively connected.

27. The method of claim 26, wherein automatically instructing a user, via the user interface, to attach one or more additional pressure measurement apparatus is performed without requiring a user to confirm, via the user interface, that the first pressure measurement apparatus is operatively connected.

28. The method of claim 24, wherein the method further comprises operating a different valve for each of the one or more pressure measurement apparatus to allow provision of air from the air pump apparatus to be used for determining whether the respective pressure measurement apparatus has been operatively commented.

29. The method of claim 24, wherein providing the one or more pressure measurement apparatus comprises providing a predetermined number of pressure measurement apparatus to be operatively connected, and further wherein the method comprises:

detecting, during a period of time, whether each of the predetermined number of pressure measurement apparatus have been operatively connected; and

alerting a user if all of the predetermined number of pressure measurement apparatus have not been operatively connected during the period of time.

30. A method of connecting an open line element of an extracorporeal blood set to a housing of an extracorporeal system, wherein the system housing contains one or more pressure transducers and an air pump apparatus, and further wherein the system comprises connection apparatus comprising at least one port to connect the open line element to at least one pressure transducer of the one or more pressure transducers, wherein the method comprises:

providing at least one open line element configured to be mounted on the system housing, wherein the open line element is operatively connectable to at least one pressure transducer of the one or more pressure transducers such that a pressure therein is measureable using the at least one pressure transducer;

controlling injection of pressurized air to the at least one port of the one or more ports using the air pump apparatus and within the open line element when mounted on the system housing; and

monitoring a rate of decay of pressure of the injected air to determine whether the open line element is operatively connected to the system housing.

31. The method of claim 30, wherein monitoring a rate of decay of pressure of the injected air comprises:

determining a pressure difference integral of the injected air over a period of time following the injection of pressurized air to the port;

comparing the pressure difference integral to a predetermined pressure integral threshold; and

detecting that the open line element is operatively connected if the pressure difference integral satisfies the predetermined pressure integral threshold.

32. The method of claim 31, wherein controlling injection of pressurized air to the at least one port comprises:

closing a valve in a line to the at least one port to increase pressure in the line; and

opening the valve to release pressurized air through the at least one port.

33. The method of claim 32, wherein determining the pressure difference integral comprises integrating the difference between the pressure of air through the port upon release of the pressurized air therethrough and an initial pressure value at the port prior to release of the pressurized air.

34. The method of claim 30, wherein the method further comprises automatically instructing a user, via a user interface, to perform one or more additional tasks if the open line element is operatively connected, without requiring a user to confirm, via the user interface, that the open line element is operatively connected.