Remote monitoring of analyte measurements

• US 9,854,972 B2
• Filed: 12/30/2013
• Issued: 01/02/2018
• Est. Priority Date: 12/31/2012
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Mensinger, Michael Robert, Cohen, Eric, Mayou, Phil, Reihman, Eli, Koehler, Katherine Yerre, Draeger, Rian, Traven, Angela Marie
• Primary Examiner(s): Phan, Hai
• Assistant Examiner(s): BALSECA, FRANKLIN D
• Application Number:
  US14/144,532
• Publication Number:
  US 20140187890A1
• Time in Patent Office: 1,464 Days
• Field of Search: 34087001, 34087002, 34087007, 705 2, 705 3, 600300, 600301, 600316, 600365, 600421, 600522, 607 28, 607 30
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/0015 characterised by features of the telemetry system
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/0024 for multiple sensor units attached to the patient, e.g. using a body or personal area network
• CPC Class Codes: A61B 5/02 Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61B 5/7435 Displaying user selection data, e.g. icons in a graphical user interface
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: A61B 5/7465 Arrangements for interactive communication between patient and care services, e.g. by using a telephone network telemetry of measured physiological signal A61B5/0002
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 20/00 ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
• CPC Class Codes: G16H 20/40 : relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• CPC Class Codes: G16H 40/20 : for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
• CPC Class Codes: G16H 40/63 : for local operation
• CPC Class Codes: G16H 40/67 : for remote operation
• CPC Class Codes: G16H 50/20 : for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/70 : for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: H04L 67/12 : specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
• CPC Class Codes: H04Q 2209/00 : Arrangements in telecontrol or telemetry systems
• CPC Class Codes: H04Q 2209/10 : using a centralized architecture
• CPC Class Codes: H04Q 2209/40 : using a wireless architecture
• CPC Class Codes: H04Q 2209/50 : using a mobile data collecting device, e.g. walk by or drive by
• CPC Class Codes: H04Q 2209/70 : Arrangements in the main station, i.e. central controller
• CPC Class Codes: H04Q 9/00 : Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

Methods and apparatus, including computer program products, are provided for remote monitoring. In some example implementations, there is provided a method. The method may include receiving, at a remote monitor, a notification message representative of an event detected, by a server, from analyte sensor data obtained from a receiver monitoring an analyte state of a host; presenting, at the remote monitor, the notification message to activate the remote monitor, wherein the remote monitor is configured by the server to receive the notification message to augment the receiver monitoring of the analyte state of the host; accessing, by the remote monitor, the server, in response to the presenting of the notification message; and receiving, in response to the accessing, information including at least the analyte sensor data. Related systems, methods, and articles of manufacture are also disclosed.

Claims

1. A method for remotely monitoring glucose concentration for a plurality of hosts by any number of remote wireless mobile computing devices in communication with a remote server system, the remote server system storing glucose concentration data for each of the plurality of hosts, the glucose concentration data of each host being measured by a different glucose monitoring system, the method comprising:

authorizing, at the remote server system, a request from a first remote monitoring application installed on a first remote wireless computing device to receive glucose information of a first host;

authorizing, at the remote server system, a request from a second remote monitoring application installed on a second remote wireless computing device to receive glucose information of a second host;

establishing, at the remote server system, a plurality of rule sets, a first rule set of the plurality of rule sets being defined by the first host and that can be modified by a first user using the first remote monitoring application, a second rule set of the plurality of rule sets being defined by the second host and that can be modified by a second user using the second remote monitoring application, wherein the first rule set comprises a first threshold value associated with a first host'"'"'s glucose concentration and wherein the second rule set comprises a second threshold value associated with a second host'"'"'s glucose concentration, and wherein the first threshold value is different from the second threshold value;

determining, by the remote server system, that the at least some glucose concentration data indicative of the first host'"'"'s glucose concentration received from the first host'"'"'s glucose monitoring system exceeds or is below the first threshold value;

generating, by the remote server system, a first alert informative of an event based on the determination that the at least some of the glucose concentration data indicative of the first host'"'"'s glucose concentration exceeds or is below the first threshold value;

transmitting, by the remote server system, the first alert to the first remote wireless computing device, wherein the first remote wireless computing device is configured to display the notification alert regardless of whether the first remote monitoring application is active or inactive on the first remote wireless computing device and activate the first remote monitoring application if the first remote monitoring application is inactive;

receiving and confirming, by the remote server system, a first acknowledgement from the first remote monitoring application indicating that the first user has received the first alert, the remote server system not providing additional glucose concentration data indicative of the first user'"'"'s glucose concentration to the first remote monitoring application until the first acknowledgement is confirmed;

determining, by the remote server system, that the at least some glucose concentration data indicative of the second host'"'"'s glucose concentration received from the second host'"'"'s glucose monitoring system exceeds or is below the second threshold value;

generating, by the remote server system, a second alert informative of an event based on the determination that the at least some of the glucose concentration indicative of the second host'"'"'s glucose concentration data exceeds or is below the second threshold value;

transmitting, by the remote server system, the second alert to the second remote wireless computing device, wherein the second remote wireless computing device is configured to display the alert regardless of whether the second remote monitoring application is active or inactive on the second remote wireless computing device and activate the second remote monitoring application if the second remote monitoring application is inactive; and

receiving and confirming, by the remote server system, a second acknowledgement from the second remote monitoring application indicating that the second user has received the second alert, the remote server system not providing additional glucose concentration data indicative of the second user'"'"'s glucose concentration to the second remote monitoring application until the second acknowledgement is confirmed.

2. The method of claim 1, wherein the first and second remote wireless computing devices are smartphones.

3. The method of claim 1, wherein the first alert is a text message.

4. The method of claim 1, wherein the first host'"'"'s glucose monitoring system comprises a continuous glucose sensor, a sensor electronics module attached to the glucose sensor, and a receiver in wireless communication with the sensor electronics module, wherein the sensor electronics module intermittently transmits the at least some of the glucose concentration data indicative of the first host'"'"'s glucose concentration to the receiver;

and the receiver intermittently transmits the at least some of the glucose concentration data indicative of the first host'"'"'s glucose concentration to the remote server.

5. The method of claim 4, wherein the receiver is a smart mobile communication device with an application downloaded thereon to receive sensor data from the transmitter and transmit the sensor data to the remote server.

6. The method of claim 4, further comprising:

applying, by the receiver, a plurality of predefined thresholds to the sensor data; and

triggering a user-perceptible alarm when the sensor data satisfies one or more of the plurality of predefined thresholds.

7. The method of claim 1, further comprising configuring the first rule set of the plurality of rule sets based on configuration parameters received from the first remote monitoring application, the configuration parameters including the first threshold value.

8. The method of claim 1, the first rule set additionally comprises a loss of data rule, the method further comprising:

determining, by the remote server system, if the loss of data rule is satisfied when the remote server system does not receive the glucose concentration data indicative of the first host'"'"'s glucose concentration from the first host'"'"'s glucose monitoring system for a predetermined amount of time;

transmitting, by the remote server system, a third alert indicating loss of data from the first host'"'"'s glucose monitoring system to the first remote wireless computing device, the first host'"'"'s glucose monitoring system, or both.

9. The method of claim 8, wherein the predetermined amount of time for the first rule set is user-configurable by the first remote monitoring application.

10. The method of claim 1, wherein the first rule set is configurable by the first remote wireless computing device but not the second remote wireless computing device, and the second rule set is configurable by the second remote wireless computing device but not the first remote wireless computing device.

11. The method of claim 1, wherein the first concentration value and second concentration values are hypoglycemia thresholds, wherein the hypoglycemia threshold for the first concentration value is different than the hypoglycemia threshold for the second concentration value.

12. The method of claim 1, wherein the first concentration value and second concentration values are hyperglycemia thresholds, wherein the hyperglycemia threshold for the first concentration value is different than the hyperglycemia threshold for the second concentration value.

13. The method of claim 1, wherein each of the first threshold value and the second threshold value thresholds comprise a threshold selected from the group consisting of a low glucose threshold, a high glucose threshold and a glucose rate of change threshold.

14. The method of claim 1, wherein the first remote wireless mobile computing device is invited by the first host to remotely monitor the glucose information of the first host prior to authorizing the request from the first remote monitoring application installed on the first remote wireless computing device, and wherein the first remote wireless mobile computing device is invited by receiving an invitation generated by the remote server system.

15. The method of claim 14, wherein the invitation generated by the remote server generated system includes a code associated with both the first remote wireless computing device and a computing device of the first host in communication with the glucose monitoring system of the first host, and wherein authorizing the request from the first remote monitoring application is at least partially contingent upon the remote server system receiving the code in a communication from the first remote wireless computing device.

16. The method of claim 14, wherein the invitation is associated with a set of recommended rule settings for the first remote wireless computing device configured by the first host using a receiver device of the first host'"'"'s glucose monitoring system, wherein the recommended rule settings are provided to the first remote wireless computing device for acceptance or modification for establishment of the first rule set corresponding to the first remote wireless computing device.

17. The method of claim 1, wherein generating, by the remote server system, the first alert informative of the event based on the determination that the at least some of the glucose concentration data indicative of the first host'"'"'s glucose concentration exceeds or is below the first threshold value comprises generating, by the remote server system, the first alert informative of the event based on the determination that the at least some of the glucose concentration data indicative of the first host'"'"'s glucose concentration exceeds or is below the first threshold and satisfaction of a second rule of the first rule set.

18. The method of claim 1, wherein the first alert indicates an urgently low glucose concentration, a low glucose concentration, or a high glucose concentration.

19. The method of claim 1, wherein the first alert is transmitted to the first remote wireless computing device and a third remote wireless computing device.

20. The method of claim 1, further comprising providing, by the remote server system to the first remote wireless computing device, past glucose concentration data indicative of the first host'"'"'s glucose concentration previously received from the first host'"'"'s glucose monitoring system to enable the first remote monitoring application to display a glucose trend graph of the first host'"'"'s glucose concentration data on a display of the first remote wireless computing device.