Method and system for management of diabetes with a glucose monitor and infusion pump to provide feedback on bolus dosing

• US 9,861,747 B2
• Filed: 12/05/2013
• Issued: 01/09/2018
• Est. Priority Date: 12/05/2013
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Inventors: Chovanda, Sweta, Morales, Carlos Omar
• Primary Examiner(s): FLICK, JASON E
• Application Number:
  US14/098,353
• Publication Number:
  US 20150157792A1
• Time in Patent Office: 1,496 Days
• Field of Search: 604504
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 80/00 ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed into the controller. The infusion pump is configured to deliver insulin to a subject. The system provides the user with the ability to understand the effects of bolus insulin dosing upon their glucose levels. Specifically, the system provides a message that must include: (a) the trend of the user'"'"'s glucose; (b) the recommended bolus; and (c) the actual bolus.

Claims

1. A system for management of diabetes, the system comprising:

an episodic glucose meter to measure glucose level in a fluid sample of a subject at discrete non-uniform time intervals and provide such episodic glucose level as input data for calculating a bolus recommendation;

a continuous glucose monitor to continuously measure glucose level of the subject at discrete generally uniform time intervals and provide the glucose level at each interval in the form of glucose measurement data that can be used for calculating the bolus recommendation;

an insulin infusion pump to deliver insulin to the subject;

a microcontroller in communication with the pump, glucose meter and the glucose monitor in which the microcontroller is configured to provide the bolus recommendation to the subject, evaluate whether an actual bolus delivered by the pump is other than the bolus recommendation;

in the event the actual bolus delivered is other than the bolus recommendation, determine a trend of glucose values over a period of time and annunciate one of a low trend or high trend to the user simultaneously with the actual bolus delivered and the bolus recommendation.

2. The system of claim 1, in which the low trend threshold comprises a decreasing rate of glucose concentration about 20 mg/dL every thirty minutes and the high trend threshold comprises an increasing rate of change of glucose concentration of about 20 mg/dL every thirty minutes.