Compositions and methods for treating diseases of the nail

  • US 9,877,955 B2
  • Filed: 10/24/2016
  • Issued: 01/30/2018
  • Est. Priority Date: 01/03/2008
  • Status: Active Grant
First Claim
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1. A method for the treatment of onychomycosis comprising topically applying to the surface of the nail of an individual suffering from onychomycosis a pharmaceutical composition comprising:

  • 50% w/w to 70% w/w ethanol,8% w/w to 15% w/w diisopropyl adipate,8% w/w to 15% w/w C12-15 alkyl lactate,10% w/w to 15% w/w cyclomethicone, and2% w/w to 15% w/w (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidine-1-yl)-1-(1H-1,2,4-triazole-1-yl)butane-2-ol;

    wherein the composition is formulated as a solution; and

    wherein the application of the composition is in an amount and for a time sufficient to ameliorate the symptoms of the onychomycosis.

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