Motion activated septum puncturing drug delivery device

• US 9,878,091 B2
• Filed: 04/27/2015
• Issued: 01/30/2018
• Est. Priority Date: 03/26/2012
• Status: Active Grant

• Current Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: Medimop Medical Projects Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: Cabiri, Oz
• Primary Examiner(s): Stigell, Theodore
• Assistant Examiner(s): Koo, Benjamin
• Application Number:
  US14/696,644
• Publication Number:
  US 20150224253A1
• Time in Patent Office: 1,009 Days
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/14256 with means for preventing access to the needle after use
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2005/14533 cam actuated
• CPC Class Codes: A61M 2005/14573 with a replaceable reservoir for quick connection/disconnection with a driving system
• CPC Class Codes: A61M 2005/1581 Right-angle needle-type devices
• CPC Class Codes: A61M 2005/247 with fixed or steady piercing means, e.g. piercing under movement of ampoule
• CPC Class Codes: A61M 2005/2474 with movable piercing means, e.g. ampoule remains fixed or steady
• CPC Class Codes: A61M 2205/123 with incorporated reservoirs
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/158 Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/283 by telescoping of ampoules or carpules with the syringe body
• CPC Class Codes: A61M 5/3146 Priming, e.g. purging, reducing backlash or clearance
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion

Abstract

A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

Claims

1. A wearable drug delivery apparatus for administering a drug to a recipient, the drug delivery apparatus comprising:

a housing having a base surface configured to be positioned proximate the subject'"'"'s skin, the base surface having a needle opening therein;

a controlled rate power actuator;

a cartridge positioned within the housing, having a longitudinal axis being substantially parallel to the base surface, the cartridge containing the drug therein and having one of a septum or a piercing needle and the housing having the other of the septum and the piercing needle, the cartridge being movable by the power actuator from a sealed position, wherein the piercing needle is sealed by the septum, to a discharge position, wherein the piercing needle punctures through the septum;

a plunger movably mounted in the cartridge, the plunger being movable by the power actuator along the longitudinal axis;

an injection needle fluidly connectable to the cartridge and having a needle tip including an opening, the needle tip being movable by a biasing member from a retracted position, wherein the needle tip is located within the housing, to a released position, wherein the needle tip extends through the needle opening and is located outside of the housing;

a trigger arm triggering the release of the needle tip into the released position when the trigger arm is moved by the cartridge as the cartridge is moved from the sealed position to the discharge position; and

an injection needle septum positioned in the housing;

wherein the needle tip is inserted in the injection needle septum, sealing the needle tip opening in the retracted position, and the needle tip penetrates through the injection needle septum in the released position.

2. The drug delivery apparatus of claim 1, wherein the injection needle septum is positioned within the needle opening.

3. The drug delivery apparatus of claim 1, wherein the needle tip is oriented substantially perpendicular to the base surface.

4. The drug delivery apparatus of claim 1, wherein the needle tip is injected into the subject'"'"'s skin in the released position.