Multiple tunable central cathodes on a paddle for increased medial-lateral and rostral-caudal flexibility via current steering

• US 9,878,149 B2
• Filed: 11/28/2016
• Issued: 01/30/2018
• Est. Priority Date: 09/04/2008
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Moffitt, Michael A., Lee, Dongchul, Bradley, Kerry, Peterson, David K. L.
• Primary Examiner(s): Porter, Jr., Allen
• Application Number:
  US15/361,602
• Publication Number:
  US 20170072190A1
• Time in Patent Office: 428 Days
• Field of Search: 607115-117
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36071 Pain

Abstract

A neurostimulation paddle lead, method of neurostimulation, and neurostimulation system are provided. The neurostimulation paddle lead carries a plurality of electrodes comprising at least four columns of electrodes having a spacing between two inner electrode columns less than a spacing between the inner electrode columns and adjacent outer electrode columns. The inner electrode columns may also be longitudinally offset from the outer electrode columns. The methods and neurostimulation systems steer current between the electrodes to modify a medial-lateral electrical field created adjacent spinal cord tissue.

Claims

1. A neurostimulation system for providing therapy to a patient, the neurostimulation system comprising:

a neurostimulation paddle lead configured to be operably positioned for use to stimulate spinal cord tissue of the patient, the neurostimulation paddle lead carrying a plurality of electrodes comprising at least four electrodes extending in a direction transverse to a longitudinal axis of the neurostimulation paddle lead, wherein the at least four electrodes include two inner electrodes and two outer electrodes flanking the two inner electrodes; and

a neurostimulator configured to convey electrical energy between the electrodes to create a medial-lateral electrical field having a locus on a first lateral side of the midline of the spinal cord tissue, and conveying electrical energy between the electrodes to create a medial-lateral electrical field having a locus on a second lateral side of the midline of the spinal cord tissue, the neurostimulator being further configured to repeatedly move the medial lateral electrical field back and forth between the first lateral side of the midline of the spinal cord tissue and the second lateral side of the midline of the spinal cord tissue to provide stimulation of dorsal column nerve fibers on the first and second lateral sides of the midline without stimulating dorsal column nerve fibers along the midline of the spinal cord tissue.

2. The neurostimulation system of claim 1, wherein the neurostimulator is configured to convey the electrical energy between the electrodes to create the medial-lateral electrical field having a locus on the first lateral side of the midline of the spinal cord tissue by configuring only a first one of the inner electrodes as a cathode, and configured to convey the electrical energy between the electrodes to create the medial-lateral electrical field having a locus on the second lateral side of the midline of the spinal cord tissue by configuring only a second one of the inner electrodes as a cathode.

3. The neurostimulation system of claim 1, wherein the neurostimulator is configured to convey the electrical energy between the electrodes to create the medial-lateral electrical field having a locus on the first lateral side of the midline of the spinal cord tissue by configuring a first one of the inner electrodes to have more cathodic current than a second one of the inner electrodes, and configured to convey the electrical energy between the electrodes to create the medial-lateral electrical field having a locus on the second lateral side of the midline of the spinal cord tissue by configuring the second one of the inner electrodes to have more cathodic current than the first one of the inner electrodes.

4. The neurostimulation system of claim 2, wherein the neurostimulator is configured to convey the electrical energy between the cathodes and the anodes to create an electrical field that stimulates the dorsal column fibers without stimulating dorsal root fibers within the spinal cord tissue.

5. The neurostimulation system of claim 1, wherein the neurostimulator is configured to convey the electrical energy in a first timing channel to move the locus of the medial-lateral electrical field to the first lateral side of the midline of the spinal cord tissue, and configured to convey the electrical energy in a second timing channel to move the locus of the medial-lateral electrical field to the second lateral side of the midline of the spinal cord tissue.

6. The neurostimulation system of claim 1, wherein the neurostimulator is configured to repeatedly move the locus of the medial-lateral field back and forth between the first lateral side and the second lateral side of the midline of the spinal cord tissue stimulates dorsal column nerve fibers on both sides of the midline of the spinal cord tissue without stimulating the dorsal column nerve fibers along the midline of the spinal cord tissue.

7. The neurostimulation system of claim 1, wherein the two inner electrodes include at least two cathodes and the neurostimulator is further configured to incrementally shift currents between the at least two cathodes to move the medial-lateral electrical field.

8. A neurostimulation system for providing therapy to a patient, the neurostimulation system comprising:

stimulation output circuitry operably connected to electrodes and a controller operably connected to the stimulation output circuitry to provide a medial-lateral electrical field having a locus on a first lateral side of a midline of spinal cord tissue, and to create a medial-lateral electrical field having a locus on a second lateral side of the midline of the spinal cord tissue, and repeatedly move the medial-lateral electrical field back and forth between the first lateral side of the midline of the spinal cord tissue and the second lateral side of the midline of the spinal cord tissue to provide stimulation of dorsal column nerve fibers on the first and second lateral sides of the midline without stimulating dorsal column nerve fibers along the midline of the spinal cord tissue.

9. The neurostimulation system of claim 8, wherein only a first portion of the electrodes is provided as a cathode to create the medial-lateral electrical field having the locus on the first lateral side of the midline of the spinal cord tissue.

10. The neurostimulation system of claim 9, wherein only a second portion of the electrodes is provided as a cathode to create the medial-lateral electrical field having the locus on the second lateral side of the midline of the spinal cord tissue.

11. The neurostimulation system of claim 8, wherein the controller is operably connected to the stimulation output circuitry to create the medial-lateral electrical field having the locus on the first lateral side of the midline of the spinal cord tissue by configuring a first one of the electrodes to have more cathodic current than a second one of the electrodes, and to create the medial-lateral electrical field having a locus on the second lateral side of the midline of the spinal cord tissue by configuring the second one of the electrodes to have more cathodic current than the first one of the electrodes.

12. The neurostimulation system of claim 11, wherein the controller is operably connected to the stimulation output circuitry to convey the electrical energy between the first one of the electrodes and the second one of the electrodes of the means for providing to create an electrical field that stimulates the dorsal column fibers without stimulating dorsal root fibers within the spinal cord tissue.

13. The neurostimulation system of claim 8, wherein the electrical energy is conveyed in a first timing channel to move the locus of the medial-lateral electrical field to the first lateral side of the midline of the spinal cord tissue, and the electrical energy is conveyed in a second timing channel to move the locus of the medial-lateral electrical field to the second lateral side of the midline of the spinal cord tissue.

14. A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to:

(a) instruct a neurostimulator to convey electrical energy between at least four electrodes disposed adjacent spinal cord tissue of a patient in a medial-lateral electrode arrangement to create a medial-lateral electrical field, the least four electrodes including two inner electrodes and two outer electrodes flanking the two inner electrodes;

(b) instruct the neurostimulator to discretely move a locus of the medial-lateral electrical field to one lateral side of the midline of the spinal cord tissue;

(c) instruct the neurostimulator to discretely move the locus of the medial lateral electrical field to the other lateral side of the midline of the spinal cord tissue; and

(d) instruct the neurostimulator to repeat steps (b) and (c) to repeatedly move the locus of the medial-lateral field back and forth between the one lateral side and the other lateral side of the midline of the spinal cord tissue, whereby dorsal column nerve fibers on both sides of the midline of the spinal cord tissue are stimulated without stimulating dorsal column nerve fibers along the midline of the spinal cord tissue.

15. The non-transitory machine-readable medium of claim 14, wherein moving the locus of the medial-lateral electrical field to the one lateral side of the midline of the spinal cord tissue is accomplished by configuring only a first one of the inner electrodes as a cathode and configuring at least one of the outer electrodes as an anode, and wherein moving the locus of the medial-lateral electrical field to the other lateral side of the midline of the spinal cord tissue is accomplished by configuring only a second one of the inner electrodes as a cathode, and at least one of the outer electrodes as an anode.

16. The non-transitory machine-readable medium of claim 14, wherein moving the locus of the medial-lateral electrical field to the one lateral side of the midline of the spinal cord tissue is accomplished by configuring a first one of the inner electrodes to have more cathodic current than a second one of the inner electrodes, and configuring at least one of the outer electrodes as an anode, and wherein moving the locus of the medial-lateral electrical field to the other lateral side of the midline of the spinal cord tissue is accomplished by configuring the second one of the inner electrodes to have more cathodic current than the first one of the inner electrodes, and configuring at least one of the outer electrodes as an anode.

17. The non-transitory machine-readable medium of claim 15, wherein the medial-lateral electrical field stimulate the dorsal column fibers without stimulating dorsal root fibers within the spinal cord tissue.

18. The non-transitory machine-readable medium of claim 14, wherein the at least four electrodes are disposed within the epidural space of a patient.

19. The non-transitory machine-readable medium of claim 14, wherein the electrical energy is conveyed in a first timing channel to move the locus of the medial-lateral electrical field to the one lateral side of the midline of the spinal cord tissue, and the electrical energy is conveyed in a second timing channel to move the locus of the medial-lateral electrical field to the other lateral side of the midline of the spinal cord tissue.

20. The non-transitory machine-readable medium of claim 14, wherein the repeated movement of the locus of the medial-lateral field back and forth between the one lateral side and the other lateral side of the midline of the spinal cord tissue stimulates dorsal column nerve fibers on both sides of the midline of the spinal cord tissue without stimulating the dorsal column nerve fibers along the midline of the spinal cord tissue.