Systems and methods for identifying a contra-ictal condition in a subject
First Claim
1. A method of identifying a contra-ictal status of a subject, the method comprising:
- obtaining, by one or more physiological sensors, an electroencephalogram (EEG) signal dataset from the subject;
using a processor to complete steps of;
generating an N-dimensional feature vector for each of different time points of the EEG signal dataset;
identifying a grouping of contra-ictal feature vectors that is substantially free of pro-ictal feature vectors, wherein the contra-ictal feature vectors are associated with a low susceptibility of having a seizure and the pro-ictal feature vectors are associated with high susceptibility of having a seizure;
identifying a grouping of pro-ictal feature vectors that is substantially free of contra-ictal feature vectors;
using the grouping of contra-ictal feature vectors to provide an output associated with a contra-ictal status and using the grouping of pro-ictal feature vectors to provide an output associated with a pro-ictal status;
comparing the contra-ictal output to at least one threshold to determine a contra-ictal state;
comparing the pro-ictal output to at least one threshold to determine a pro-ictal state;
selecting an indicator from among at least three indicators based on the contra-ictal state and the pro-ictal state, each of the at least three indicators corresponding to a different susceptibility of having a seizure, wherein the selected indicator indicates whether the subject has the contra-ictal status; and
displaying, by a seizure advisory system, the selected indicator.
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Accused Products
Abstract
The invention provides a method of monitoring a subject'"'"'s neurological condition. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition, such as by activating a green light or other visible output. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition. The invention also provides neurological system monitors.
506 Citations
18 Claims
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1. A method of identifying a contra-ictal status of a subject, the method comprising:
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obtaining, by one or more physiological sensors, an electroencephalogram (EEG) signal dataset from the subject; using a processor to complete steps of; generating an N-dimensional feature vector for each of different time points of the EEG signal dataset; identifying a grouping of contra-ictal feature vectors that is substantially free of pro-ictal feature vectors, wherein the contra-ictal feature vectors are associated with a low susceptibility of having a seizure and the pro-ictal feature vectors are associated with high susceptibility of having a seizure; identifying a grouping of pro-ictal feature vectors that is substantially free of contra-ictal feature vectors; using the grouping of contra-ictal feature vectors to provide an output associated with a contra-ictal status and using the grouping of pro-ictal feature vectors to provide an output associated with a pro-ictal status; comparing the contra-ictal output to at least one threshold to determine a contra-ictal state; comparing the pro-ictal output to at least one threshold to determine a pro-ictal state; selecting an indicator from among at least three indicators based on the contra-ictal state and the pro-ictal state, each of the at least three indicators corresponding to a different susceptibility of having a seizure, wherein the selected indicator indicates whether the subject has the contra-ictal status; and displaying, by a seizure advisory system, the selected indicator. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method of identifying a contra-ictal status of a subject, the method comprising:
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obtaining, by one or more physiological sensors, an electroencephalogram (EEG) signal dataset from the subject, the EEG signal dataset including contra-ictal data corresponding to a contra-ictal status of the subject in which the subject has a low susceptibility of having a seizure for a time period, the EEG signal dataset further including pro-ictal data corresponding to a pro-ictal status of the subject in which the subject has a high susceptibility of having a seizure; using a processor to complete steps of; distinguishing the contra-ictal data from the pro-ictal data within the EEG signal dataset; providing an output associated with the contra-ictal status and providing an output associated with the pro-ictal status based on the distinguished data; comparing the contra-ictal output to at least one threshold to determine a contra-ictal state; comparing the pro-ictal output to at least one threshold to determine a pro-ictal state; selecting an indicator from among at least three indicators based on the contra-ictal state and the pro-ictal state, each of the at least three indicators corresponding to a different susceptibility of having a seizure, wherein the selected indicator indicates whether the subject has the contra-ictal status; displaying, by a seizure advisory system, the selected indicator; and reporting, by the processor, the contra-ictal status of the subject. - View Dependent Claims (11, 12, 13, 14, 15)
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16. A method of identifying a contra-ictal status of a subject, the method comprising:
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obtaining, by one or more physiological sensors, an electroencephalogram (EEG) signal dataset from the subject, the EEG signal dataset corresponding to a normal non-seizure status of the subject; using a processor to complete steps of; distinguishing contra-ictal data from pro-ictal data within the EEG signal dataset, wherein the contra-ictal data is associated with a low susceptibility of having a seizure and the pro-ictal data is associated with a high susceptibility of having a seizure; in response to distinguishing the contra-ictal data from the pro-ictal data, providing an output associated with a contra-ictal status for a time period and providing an output associated with a pro-ictal status for the time period, the time period being a future period of time; comparing the contra-ictal output to at least one threshold to determine a contra-ictal state for the time period; comparing the pro-ictal output to at least one threshold to determine a pro-ictal state for the time period; selecting an indicator from among at least three indicators based on the contra-ictal state and the pro-ictal state, each of the at least three indicators corresponding to a different susceptibility of having a seizure for the time period, wherein the selected indicator indicates whether the subject has the contra-ictal status; and displaying, by a seizure advisory system, the selected indicator. - View Dependent Claims (17, 18)
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Specification