Orally disintegrable tablets

  • US 9,901,546 B2
  • Filed: 05/27/2014
  • Issued: 02/27/2018
  • Est. Priority Date: 05/18/1998
  • Status: Active Grant
First Claim
Patent Images

1. An orally disintegrable tablet, which comprises:

  • (i) fine granules comprising a composition coated with an enteric coating layer, said composition comprising;

    10 weight % or more of lansoprazole or a salt thereof relative to the composition; and

    a basic inorganic salt selected from the group consisting of a salt of magnesium and a salt of calcium; and

    (ii) an additive comprising crospovidone and a water-soluble sugar alcohol,wherein the water-soluble sugar alcohol is comprised in the tablet separately from the fine granules,the enteric coating layer is about 30-70 weight % relative to the fine granule,the enteric coating layer comprises a methacrylic acid copolymer as an aqueous enteric polymer agent,the orally disintegrable tablet is administerable without water, an oral disintegration time of the orally disintegrable tablet is one minute or less,the orally disintegrable tablet is not an effervescent, andthe composition does not comprise alkaline metal carbonate.

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