Inhibition of HIV infection through chemoprophylaxis

  • US 9,937,191 B2
  • Filed: 01/13/2017
  • Issued: 04/10/2018
  • Est. Priority Date: 02/03/2006
  • Status: Active Grant
First Claim
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1. A process of protecting a primate host from a self-replicating infection by an immunodeficiency retrovirus comprising:

  • (a) selecting a primate host not infected with the immunodeficiency retrovirus, and(b) administering directly to an uninfected primate host a combination comprising;

    i. a pharmaceutically effective amount of emtricitabine; and

    ii. a pharmaceutically effective amount of tenofovir or tenofovir disoproxil fumarate,wherein the combination is administered orally in tablet form prior to the exposure of the primate host to the immunodeficiency retrovirus,thereby protecting the primate host from infection with the immunodeficiency retrovirus.

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