Fast responsive personalized thermometer

• US 9,939,334 B2
• Filed: 11/20/2014
• Issued: 04/10/2018
• Est. Priority Date: 12/05/2013
• Status: Active Grant

• Current Assignee: Medisim Limited
• Original Assignee: Medisim Limited
• Inventors: Yarden, Moshe
• Primary Examiner(s): YUSHIN, NIKOLAY K
• Application Number:
  US14/548,633
• Publication Number:
  US 20150160079A1
• Time in Patent Office: 1,237 Days
• CPC Class Codes: G01K 13/20 Clinical contact thermometers for use with humans or animals
• CPC Class Codes: G01K 17/00 Measuring quantity of heat measuring temperature by calorimetry G01K3/00 - G01K11/00; specially adapted for measuring thermal properties of materials, e.g. specific heat, heat of combustion G01N
• CPC Class Codes: G01K 7/42 Circuits effecting compensation of thermal inertia; Circuits for predicting the stationary value of a temperature

Abstract

A thermometer includes a processing unit configured to receive a plurality of timed apart temperature readings from first and second sensors and a processor calculates heat flux value, Q, and obtains values of the heat flux vs. temperature (Q vs. T_s.) as the temperature approaches a steady state. The processor empirically predicts the steady state temperature of the sensor Ts, using the peak value of the values of Q vs. T_s.

The processor may also empirically calculate a bias value as a function of the peak value of Q vs. T_s. The bias value represents the difference between the temperature reading (T_s) at steady state and core temperature of the subject and is added to the steady state temperature to arrive at core. The thermometer probe may include one or more additional sensors for obtaining physiological readings from the subject other than temperature and the processing unit is configured to use empirical formulas to calculate the bias value using the physiological readings which may include blood perfusion, pulse rate and the bio-impedance of the subject.

Claims

1. A thermometer for determining an internal temperature of a subject comprising:

a probe;

a first sensor forming a part of the probe and configured to obtain temperature readings from an external surface of the subject; and

a processing unit configured to receive a plurality of timed apart temperature readings, Ts, from the first sensor;

to calculate a value of the heat flux (Q) flowing from the subject to the first sensor;

to determine a peak value of Q and a corresponding value of Ts; and

to utilize the peak value of Q and the corresponding value of Ts to determine the internal temperature of the subject.

2. The thermometer in accordance with claim 1 wherein the processing unit is further configured to predict a steady state temperature of first temperature sensor.

3. The thermometer in accordance with claim 1 wherein said subject'"'"'s temperature is monitored continuously and said values of Q vs. Ts are obtained prior toTs reaching its steady state value.

4. The thermometer in accordance with claim 1 wherein the processing unit is further configured to calculate a bias value representing a difference between a clinically acceptable proximation of a core temperature of the subject and a local temperature of the subject at a measuring site as a function of the peak value of Q vs. Ts. and to use the bias value to arrive at the core temperature of the subject.

5. The thermometer in accordance with claim 4 wherein the local temperature is a steady state temperature of the first sensor.

6. The thermometer in accordance with claim 5 wherein the first sensor is a thermistor and the local temperature represents a deep tissue temperature at the measuring site.

7. The thermometer in accordance with claim 5 wherein the first sensor is an IR sensor and the local temperature is a skin temperature of the subject at the measuring site.

8. The thermometer in accordance with claim 1 wherein the probe includes a surface for contacting the subject, the first sensor is proximal said surface and further including a second sensor spaced apart from the first sensor and distal said surface wherein said heat flux (Q) is determined at each time interval as a function of the difference between the temperature readings Ts from the first sensor and readings Tr from the second sensor.

9. The thermometer in accordance with claim 8 wherein the first sensor and the second sensor are aligned generally perpendicular to the surface for contacting the subject.

10. The thermometer in accordance with claim 8 wherein the first sensor and the second sensor are offset from one another in a direction orthogonal to a perpendicular to the surface for contacting the subject.

11. The thermometer in accordance with claim 8 wherein at least one of said first and second sensors comprise thermistors.

12. The thermometer in accordance with claim 8 wherein said subject'"'"'s temperature is monitored continuously and said values of Q vs. Ts are obtained prior to Ts reaching its steady state value.

13. A thermometer comprising:

a probe;

a temperature sensor forming a part of said probe and configured to obtain temperature readings from a subject at a measuring site; and

a processing unit configured

to obtain said temperature readings from the subject and from said temperature readings to determine a steady state temperature of the temperature sensor at the measuring site;

to obtain physiological readings from a non-temperature sensor and to empirically calculate a bias value as a function of said physiological readings, said bias value representing a difference between the said determined steady state temperature of the sensor and the core temperature of the subject;

to use the bias value and the said determined steady state temperature to arrive at the core temperature; and

wherein said non-temperature sensor is configured to measure a bio-impedance or a blood perfusion of the subject and said bias value is calculated as a function of the measured bio-impedance or blood perfusion.

14. The thermometer in accordance with claim 13 wherein said temperature sensor is a thermistor.

15. The thermistor in accordance with claim 13 wherein said temperature sensor is an IR sensor.

16. The thermometer in accordance with claim 13 wherein said non-temperature sensor forms another part of said probe and is configured to obtain physiological readings from said subject at the same measuring site as that for obtaining said subject'"'"'s temperature.

17. The thermometer in accordance with claim 13 wherein said subject'"'"'s temperature is monitored continuously and said values of Q vs. Ts are obtained prior to Ts reaching its steady state value.

18. The thermometer in accordance with claim 13 wherein said non-temperature sensor is a photoplethysmogram (PPG).

19. The thermometer in accordance with claim 18 wherein said photoplethysmogram produces a signal having an AC component synchronous with a subject'"'"'s pulse rate and a DC component wherein said bias value is calculated as a function of a subject'"'"'s pulse rate.

20. The thermometer in accordance with claim 19 wherein said bias value is calculated as a function of a subject'"'"'s pulse rate and a measured blood perfusion.