Cardiac stimulation using intravascularly-deliverable electrode assemblies

• US 9,956,401 B2
• Filed: 01/23/2014
• Issued: 05/01/2018
• Est. Priority Date: 09/13/2006
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Hastings, Roger, Lafontaine, Daniel M., Pikus, Michael J., Willard, Martin R.
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): So, Elizabeth K
• Application Number:
  US14/162,446
• Publication Number:
  US 20140135865A1
• Time in Patent Office: 1,559 Days
• Field of Search: 607 32
• CPC Class Codes: A61N 1/059 Anchoring means
• CPC Class Codes: A61N 1/365 controlled by a physiological parameter, e.g. heart potential evoked response A61N1/371
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/37288 Communication to several implantable medical devices within one patient
• CPC Class Codes: A61N 1/375 Constructional arrangements, e.g. casings
• CPC Class Codes: A61N 1/37512 Pacemakers
• CPC Class Codes: A61N 1/37518 Anchoring of the implants, e.g. fixation
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

A seed assembly for delivery to an interior of a heart includes an electrical stimulation circuit for delivering an electrical stimulus to cardiac tissue. A first electrode assembly is mechanically and electrically coupled to the seed assembly via a micro lead, the first electrode assembly configured to deliver the electrical stimulus generated by the electrical stimulation circuit to the cardiac tissue. The seed assembly and the first electrode assembly are sized and shaped to fit entirely within the heart.

Claims

1. A cardiac tissue excitation system, comprising:

a seed assembly having a housing that is sized and shaped for delivery to an interior of a heart and configured to be endocardially affixed to a wall of the heart, the seed assembly including an electrical stimulation circuit disposed within the housing for generating an electrical stimulus;

two or more electrode assemblies mechanically and electrically coupled to the seed assembly via two or more leads, a first of the two or more electrode assemblies configured to be affixed at a first location along an interior surface of the heart, a second of the two or more electrode assemblies configured to be affixed at a second location along the interior surface of the heart, wherein the second location is laterally spaced along the interior surface of the heart from the first location, the two or more leads configured to deliver electrical stimulus generated by the electrical stimulation circuit to corresponding ones of the two or more electrode assemblies, and the two or more electrode assemblies each configured to deliver the received electrical stimulus, generated by the electrical stimulation circuit, to corresponding cardiac tissue;

wherein each of the two or more electrode assemblies include a fixation element configured to anchor each of the two or more electrode assemblies to the heart; and

wherein the seed assembly and the two or more electrode assemblies are sized and shaped to fit entirely within the heart.

2. The cardiac tissue excitation system of claim 1, wherein:

the first of the two or more electrode assemblies and the second of the two or more electrode assemblies are configured to be affixed on an interior heart chamber wall.

3. The cardiac tissue excitation system of claim 2, wherein the first location includes a ventricular free wall and the second location includes a septum.

4. The cardiac tissue excitation system of claim 1, wherein the first electrode assembly of the two or more electrode assemblies is mechanically coupled a first end of the seed assembly and the second electrode assembly of the two or more electrode assemblies is mechanically coupled to a second end of the seed assembly opposite the first end.

5. The cardiac tissue excitation system of claim 1, wherein the seed assembly includes a receiver configured to receive communications wirelessly from a controller.

6. The cardiac tissue excitation system of claim 5, wherein the communications include pacing amplitude information or pacing pulse width information.

7. The cardiac tissue excitation system of claim 1, wherein the two or more electrode assemblies are independently selectable for delivering of electrical stimulation in a coordinated fashion.

8. The cardiac tissue excitation system of claim 1, wherein the seed assembly includes a sense circuit tor sensing electrical cardiac activity and a transmitter for wirelessly transmitting information associated with the sensed electrical cardiac activity.

9. A cardiac tissue excitation system, comprising:

a seed assembly including a seed housing supporting an exposed seed electrode, the seed housing sized and shaped for delivery to an interior of a heart and configured to be endocardially affixed to a first location along an interior surface of the heart, the seed assembly including an electrical stimulation circuit disposed within the seed housing for generating an electrical stimulus;

a first electrode assembly including a pacing electrode, the first electrode assembly mechanically and electrically coupled to the seed assembly via a lead, wherein the lead is configured to deliver the electrical stimulus generated by the electrical stimulation circuit of the seed assembly to the first electrode assembly and the first electrode assembly is configured to deliver the electrical stimulus to the pacing electrode of the first electrode assembly, the first electrode assembly is configured to be disposed at a second location along the interior surface of the heart, wherein the second location is laterally spaced along the interior surface of the heart from the first location, the first electrode assembly and the seed assembly are configured to deliver the electrical stimulus generated by the electrical stimulation circuit of the seed assembly to cardiac tissue via the pacing electrode of the electrode assembly and the seed electrode of the seed assembly;

wherein the first location is located at a first interior wall of the heart;

wherein the second location is located at a second interior wall of the heart different than the first interior wall of the heart; and

wherein the seed assembly and the electrode assembly are sized and shaped to fit entirely within the heart.

10. The cardiac tissue excitation system of claim 9, wherein the first interior wall includes a ventricular free wall and the second interior wall includes a septum.

11. The cardiac tissue excitation system of claim 9, wherein the first interior wall includes a septum and the second interior wall includes a ventricular free wall.

12. The cardiac tissue excitation system of claim 9, wherein the first electrode assembly includes a fixation element configured to anchor the first electrode assembly at the second location.

13. The cardiac tissue excitation system of claim 12, wherein the fixation element includes a helical tine.

14. The cardiac tissue excitation system of claim 9, wherein the seed assembly includes a receiver configured to receive communications wirelessly from a controller.

15. The cardiac tissue excitation system of claim 9, wherein the seed assembly includes a sense circuit for sensing electrical cardiac activity.

16. A cardiac tissue excitation system, comprising:

a seed assembly including a seed housing supporting an exposed seed electrode, the seed housing sized and shaped for delivery to an interior of a heart and configured to be endocardially affixed at a first location on an interior surface of a chamber of the heart, the seed assembly including an electrical stimulation circuit disposed within the seed housing for actively generating an electrical stimulus;

a first electrode assembly including a pacing electrode, the first electrode assembly mechanically and electrically coupled to the seed assembly via a lead and configured to be affixed at a second location along the interior surface of the chamber of the heart, wherein the second location is remote from the first location, wherein the lead is configured to deliver the electrical stimulus generated by the electrical stimulation circuit to the first electrode assembly and the first electrode assembly is configured to deliver the electrical stimulus directly to the pacing electrode of the first electrode assembly, the first electrode assembly and the seed assembly are configured to deliver the electrical stimulus generated by the electrical stimulation circuit of the seed assembly to cardiac tissue via the pacing electrode of the first electrode assembly and the seed electrode of the seed assembly.

17. The cardiac tissue excitation system of claim 16, wherein the first location is located at a first interior heart chamber wall and the second location is located at a second interior heart chamber wall different than the first interior heart chamber wall.

18. The cardiac tissue excitation system of claim 16, wherein the first electrode assembly includes a helical tine configured to anchor the first electrode assembly to the heart.

19. The cardiac tissue excitation system of claim 16, wherein the seed assembly includes a sense circuit for sensing electrical cardiac activity.

20. The cardiac tissue excitation system of claim 16, wherein the seed assembly includes a receiver configured to receive communications wirelessly from a controller.