Systems and methods for analyzing electrical stimulation and selecting or manipulating volumes of activation
First Claim
1. A system for identifying portions of a body in which electrical stimulation of that portion of the body to treat a condition or disorder affects at least one of at least one symptom of the condition or disorder, stimulation effect, or side effect, the system comprising:
- a computer processor configured and arranged to perform the following acts;
obtaining, for each of a plurality of stimulation instances, an estimation of a region of the body stimulated during the stimulation instance and a score for each of at least one symptom of the condition or disorder, stimulation effect, or stimulation side effect;
determining, for each of a plurality of portions of the body using the scores and the estimates in a permutation test, a likelihood that stimulation of that portion of the body affects at least one symptom of the condition or disorder, stimulation effect, or stimulation side effect; and
storing or displaying the determined likelihoods to identify which portions of the body, when electrically stimulated, affect the at least one of the at least one symptom of the condition or disorder, stimulation effect, or stimulation side effect.
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Accused Products
Abstract
A system for identifying potential portions of a body in which electrical stimulation to treat a condition or disorder affects at least one symptom of the condition or disorder, stimulation effect, or side effect performs the following acts: obtaining, for each of multiple stimulation instances, an estimation of a region of the body stimulated during the stimulation instance and a score for each of at least one symptom, stimulation effect, or stimulation side effect; and determining, for each of multiple portions of the body using the scores and the estimates in a permutation test, a likelihood that stimulation of that portion of the body affects at least one symptom, stimulation effect, or stimulation side effect. In other embodiments, the system sets up a relationship between the outcomes of stimulation and influence of a particular part of the body on the outcome, and derives this influence using a pseudoinverse.
417 Citations
9 Claims
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1. A system for identifying portions of a body in which electrical stimulation of that portion of the body to treat a condition or disorder affects at least one of at least one symptom of the condition or disorder, stimulation effect, or side effect, the system comprising:
a computer processor configured and arranged to perform the following acts; obtaining, for each of a plurality of stimulation instances, an estimation of a region of the body stimulated during the stimulation instance and a score for each of at least one symptom of the condition or disorder, stimulation effect, or stimulation side effect; determining, for each of a plurality of portions of the body using the scores and the estimates in a permutation test, a likelihood that stimulation of that portion of the body affects at least one symptom of the condition or disorder, stimulation effect, or stimulation side effect; and storing or displaying the determined likelihoods to identify which portions of the body, when electrically stimulated, affect the at least one of the at least one symptom of the condition or disorder, stimulation effect, or stimulation side effect. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
Specification