Improved pharmaceutical formulations

Improved pharmaceutical formulations

  • CN 100,418,527 C
  • Filed: 05/25/2000
  • Issued: 09/17/2008
  • Est. Priority Date: 06/04/1999
  • Status: Active Grant
First Claim
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1. pharmaceutical composition, it comprises a kind of solution, wherein contains:

  • (a) (2S, 3S, 5S)-5-(N-(N-((N-methyl-N-((2-isopropyl-4-thiazolyl) methyl) amino) carbonyl) valyl) amino)-2-(N-((5-thiazolyl) methoxycarbonyl) amino)-1,6-diphenyl-3-hydroxyl hexane, its consumption is the 1%-50% that accounts for described solution weight;

    (b) a kind of pharmaceutically useful organic solvent, wherein contain the pharmaceutically acceptable long-chain fatty acid that (i) accounts for described solution weight 30-75%, or the (ii) mixture of following material;

    account for described solution weight 30-75% pharmaceutically acceptable long-chain fatty acid and account for the ethanol of described solution weight 1-15%;

    (c) account for the water of described solution weight 0.4-3.5%;

    With(d) account for the pharmaceutically acceptable surfactant of described solution weight 0-40%.

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