Novel formulations of pharmacological agents, method for preparation thereof and method for use thereof

Novel formulations of pharmacological agents, method for preparation thereof and method for use thereof

  • CN 100,462,066 C
  • Filed: 06/26/1998
  • Issued: 02/18/2009
  • Est. Priority Date: 06/27/1997
  • Status: Active Grant
First Claim
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1. One or more of paclitaxel and its derivant and at least a protein be used for preparing comprise a part with described at least a protein bound and other parts by described one or more the purposes of pharmaceutically acceptable preparation of the unbodied paclitaxel of described at least a protein bag quilt and its derivant, wherein said preparation is suitable for the experimenter that whole body is accepted described one or more treatments of usefulness paclitaxel and its derivant, toxicity with reduction, paclitaxel and its derivant described one or more with 135mg/m at least 2Dosage, administration in the administration time that is no more than 2 hours, wherein said preparation does not contain poly-ethoxy Oleum Ricini, and described preparation comprises described one or more the granule of described unbodied paclitaxel and its derivant, average diameter is no more than 1 micron, and the derivant of wherein said paclitaxel is a taxotere.

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