Utilize genetically modified silkworm to produce the method for physiologically active protein matter

Utilize genetically modified silkworm to produce the method for physiologically active protein matter

  • CN 100,572,534 C
  • Filed: 03/06/2003
  • Issued: 12/23/2009
  • Est. Priority Date: 03/06/2002
  • Status: Active Grant
First Claim
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1. the manufacture method of a recombinant type cytokine, it is characterized in that:

  • making will be combined in the cytokine gene in promotor downstream of silk gland specifically expressing to be incorporated into chromosomal genetically modified silkworm between from a pair of terminal reverse sequence of transposon, after making the sericterium or silk production recombinant cytokine protein of the genetically modified silkworm that obtains, by reclaiming cytokine in sericterium or the silk;

    The promotor of wherein said silk gland specifically expressing is the base sequence shown in the 7th to the 1064th of sequence numbering 1.

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