Inhibition of factor B, the alternative complement pathway and methods related thereto

Inhibition of factor B, the alternative complement pathway and methods related thereto

  • CN 101,022,828 B
  • Filed: 02/10/2005
  • Issued: 12/10/2014
  • Est. Priority Date: 02/10/2004
  • Status: Active Grant
First Claim
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1. a separation antibody or its Fab, it is at the 3rd short consensus repeat (SCR) domain of the Factor B of the epi-position selective binding Factor B identical with anti-Factor B monoclonal antibody 1379 (PAT-6230 produces by ATCC preserving number) or selective binding people and mice, and wherein this antibody or its Fab stop the formation of C3bBb complex.

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