Cell cycle phase markers

Cell cycle phase markers

  • CN 101,052,646 B
  • Filed: 07/22/2005
  • Issued: 10/21/2015
  • Est. Priority Date: 07/23/2004
  • Status: Active Grant
First Claim
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1. polypeptide construct, it comprises detectable live cell reporter molecule and cell cycle phase dependency positioning controling element, described element is the phosphorylation dependency subcellular localization domain (PSLD) in the C-terminal Special controlling district of helicase B, described element be positioned at G1 and the S phase during change, the transposition of wherein said construct in mammalian cell shows cell cycle position, it is characterized in that described reporter molecule is less than 1000 daltonian peptide groups by molecular weight and is connected on described element.

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