Methods for vaccinating against malaria

Methods for vaccinating against malaria

  • CN 101,077,416 A
  • Filed: 10/22/2003
  • Published: 11/28/2007
  • Est. Priority Date: 10/23/2002
  • Status: Active Application
First Claim
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1. following vaccine causes purposes in the medicine of pathogen of malaria the immune people of preparation with opposing, described vaccine comprises:

  • A) contain the initiation vaccine that coding is selected from least a polynucleotide of CS protein or its segmental at least a first malaria antigen;

    WithB) contain the reinforcement vaccine of at least a polypeptide, wherein said polypeptide comprises and is selected from CS protein or its segmental at least a second malaria antigen, and described at least a second malaria antigen and described at least a first malaria antigen have at least a epi-position,Wherein cause using of vaccine and caused the CD8+T cell, cause memory and strengthen using subsequently of vaccine to the CD8+T cell that causes, widen the CD8+T cell response of initiation, and cause malaria CD8+T cell, malaria CD4+T cell and malaria production of antibodies.

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