GPR41 and modulators thereof for treatment of insulin-related disorders

GPR41 and modulators thereof for treatment of insulin-related disorders

  • CN 101,084,018 B
  • Filed: 11/01/2005
  • Issued: 12/18/2013
  • Est. Priority Date: 11/03/2004
  • Status: Active Grant
First Claim
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1. one kind for differentiating the method for glucostasis compound, and it comprises:

  • A) candidate compound is contacted with GPR41, andB) measure whether GPR41 is functional is regulated,Wherein the functional adjusting of GPR41 shows that described candidate compound is the glucostasis compound;

    Described GPR41 has the aminoacid sequence as shown in SEQ ID NO;

    2, or its variant, and described variant retains in fact the function with polypeptide of aminoacid sequence as shown in SEQ ID NO;

    2.

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