Coated drug delivery formulations

Coated drug delivery formulations

  • CN 101,087,588 B
  • Filed: 11/29/2005
  • Issued: 04/22/2015
  • Est. Priority Date: 11/30/2004
  • Status: Active Grant
First Claim
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1. manufacture is suitable for application to a method for the preparation of patient, comprising:

  • At least one phospholipid is provided;

    There is provided at least one surfactant, described surfactant is polysorbate;

    The bioactive agents of at least one poorly water-soluble is provided;

    The bioactive agents of at least one surfactant, at least one poorly water-soluble and at least one phospholipid are exposed to nonaqueous solvent;

    Remove described nonaqueous solvent, thus obtained powder;

    WithDescribed bioactive agents is not exposed to aqueous solvent with one or more coating bags by described powder, thus the particle of obtained bag quilt, one or more coatings wherein said and at least part of described powder contact, thus the obtained preparation being suitable for application to patient,And described surfactant is positioned at the phase boundary place of organic facies and aqueous phase.

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