As 2,5 and 2,6 disubstituted benzazole analogues of kinases inhibitor

As 2,5 and 2,6 disubstituted benzazole analogues of kinases inhibitor

  • CN 101,090,899 B
  • Filed: 12/22/2005
  • Issued: 09/09/2015
  • Est. Priority Date: 12/27/2004
  • Status: Active Grant
First Claim
Patent Images

1. the compound or its salt of general formula (I),formula (I) WhereinSubstituting group-Y-R 1be connected to 5-or the 6-position of benzazole;

  • X represents S, O, SO or SO independently 2;

    Y represents NR independently 2;

    A represents ←

    CO-or ←

    NR independently 8cO-, wherein ←

    refer to be connected to R 3point;

    R 2represent H independently;

    R 3represent pyridyl or phenyl independently, be optionally selected from halogen, C by one or more 1-C 6alkyl, C 1-C 6alkoxyl group and C 1-C 6the substituting group of haloalkyl replaces;

    R 4represent H independently;

    R 5represent H independently;

    R 8represent H independently;

    R 1be expressed as follows the one in group independently;

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