Nucleic acid-based compounds and methods of use thereof

Nucleic acid-based compounds and methods of use thereof

  • CN 101,113,160 A
  • Filed: 05/15/2002
  • Published: 01/30/2008
  • Est. Priority Date: 05/16/2001
  • Status: Active Application
First Claim
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1. be selected from the compound of compound 1-62 as follows or its pharmaceutically acceptable salt, compound is wherein modified by the replacement in the glycosyl group of 2 of at least one mononucleotide of described compound '"'"' position, described replacement is selected from H,-OH, amino, halogen group, or contain replacement or the unsubstituted-O-low-grade alkyl group of the saturated or unsaturated carbon atom of 1-6, contain 2-6 carbon atom-O-aromatic yl group or allyl group, wherein said-the O-alkyl, aryl or alkyl group are not substituted or are substituted:

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