Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent

Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent

  • CN 101,119,706 A
  • Filed: 02/13/2006
  • Published: 02/06/2008
  • Est. Priority Date: 02/25/2005
  • Status: Active Grant
First Claim
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1. aerosol formulations, its comprise active component, the liquefaction of at least a 20-of being selected from ketosteroid and (E)-3-(3-Acetyl-4-hydroxy-5-methoxy-phenyl)-N-(4-hydroxy-1-methyl-3-octyloxy-2-oxo-1,2-dihydro-quinolin-7-yl)-acrylamide the HFA propellant, be selected from the cosolvent of the acceptable alcohol of pharmacy and be selected from phosphoric acid and vitriolic chelating agen, wherein improved the chemical stability of active component, condition be when active component be 8-hydroxyl-5-[(1R)-1-hydroxyl-2-[[(1R)-2-(4-methoxyphenyl)-1-Methylethyl] amino] ethyl] when-2 (1H)-quinolinones or its hydrochlorate (TA2005), chelating agen is not a phosphoric acid.

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