Application of mulberry twigs alkaloid valid target in preparing antidiabetics medicament

Application of mulberry twigs alkaloid valid target in preparing antidiabetics medicament

CN
  • CN 101,129,476 B
  • Filed: 08/21/2006
  • Issued: 07/24/2013
  • Est. Priority Date: 08/21/2006
  • Status: Active Grant
First Claim
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1. alkaloid valid target with hypoglycemic activity, it is characterized in that, this effective site is to extract from Ramulus Mori, separate and refining after the faint yellow or light brown powder that obtains, active component in the effective site is one group of polyhydroxylated alkaloid compositions, total alkaloid content accounts for the percentage by weight of extract more than 50%, wherein the polyhydroxylated alkaloid compositions is by 1-deoxynojirimycin (1) and N-methly-1-deoxynojirimycin (2), fagomine (3), 3-epi-fagomine (4), 1,4-dideoxy-1,4-imino-D-arabinitol (5), 1,4-dideoxy-1,4-imino-D-ribitol (6), calysteginB 2(7), calysteginC 1(8), 2-O-(α

  • -D-galactopyranosyl)-1-deoxynojirimycin (9), 6-O-(β

    -D-glucopyranosyl)-1-deoxynojirimycin (17), 1,4-dideoxy-1,4-imino-(at least a composition among 2-O-β

    -D-glucopyranosyl)-D-arabinitol (18), wherein, the percentage by weight of 1-deoxynojirimycin is not less than 50% of total alkaloids.

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