Process for preparation of mixtures of polypeptides using purified hydrobromic acid

Process for preparation of mixtures of polypeptides using purified hydrobromic acid

  • CN 101,166,754 A
  • Filed: 09/09/2005
  • Published: 04/23/2008
  • Est. Priority Date: 09/09/2004
  • Status: Active Grant
First Claim
Patent Images

1. acquisition is not the method that all has the mixture of the trifluoroacetyl group polypeptide of same acid sequence;

  • wherein every peptide species is basically by L-Ala;

    L-glutamic acid;

    tyrosine and trifluoroacetyl group Methionin are formed;

    wherein said mixture has the molecular-weight average that needs and wherein in described process;

    every kind basically by L-Ala;

    γ

    -benzyl L-glutamic acid;

    the mixture of the polypeptide that tyrosine and trifluoroacetyl group Methionin are formed batch go protection with hydrobromic acetic acid solution;

    described improvement comprises uses hydrobromic acetic acid solution, and described solution comprises and is less than 0.5% free bromine.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×