Novel dispersed system with docetaxel as main component

Novel dispersed system with docetaxel as main component

CN
  • CN 101,244,053 B
  • Filed: 02/16/2007
  • Issued: 12/08/2010
  • Est. Priority Date: 02/16/2007
  • Status: Active Grant
First Claim
Patent Images

1. one kind is the dispersion of Gong the injection of major constituent with the docetaxel, and it contains principal agent docetaxel, oil phase, surfactant, cosurfactant;

  • Wherein the volume ratio of oil phase and surfactant greater than 3% smaller or equal to 33%, the volume ratio of cosurfactant and surfactant more than or equal to 12.5% less than 167%, wherein surfactant is one or more the mixture in Tweens, the brejs, cosurfactant is selected from one or more the mixture in ethanol, isopropyl alcohol, propylene glycol, glycerol, the liquid polyethylene glycol, and oil phase is selected from soybean oil, Oleum Camelliae, olive oil, safflower oil, Semen Lini oil, Radix Oenotherae erythrosepalae oil, Oleum Helianthi, Oleum Arachidis hypogaeae semen, C 8

    C 18The mixture of one or more in the glyceride type of aliphatic chain, ethyl n-butyrate., isopropyl laurate, ethyl oleate, Ethyl linoleate, triacetyl glycerine, ethyl lactate, oleic acid, the coix seed oil.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×