Chinese medicinal composition for treating coronary disease, stenocardia, arrhythmia, hyperlipemia and preparation method thereof

Chinese medicinal composition for treating coronary disease, stenocardia, arrhythmia, hyperlipemia and preparation method thereof

  • CN 101,342,207 B
  • Filed: 08/22/2008
  • Issued: 04/10/2013
  • Est. Priority Date: 08/22/2008
  • Status: Active Grant
First Claim
Patent Images

1. a Chinese medicine composition for the treatment of coronary heart diseases and angina pectoris, arrhythmia, hyperlipidemia is characterized in that, makes by the following method:

  • Get Moschus 5-20 weight portion, Calculus Bovis 12-50 weight portion, sodium cholate 60-250 weight portion, Venenum Bufonis 12-50 weight portion, Margarita 30-120 weight portion, Borneolum Syntheticum 40-160 weight portion, Radix Notoginseng 1500-15000 weight portion, Radix Ginseng 150-600 weight portion, Cornu Bubali dry extract 50-200 weight portion;

    The 20-90% that gets the pseudo-ginseng amount extracts Radix Notoginseng total arasaponins, all the other Radix Notoginseng and Moschus, Calculus Bovis, sodium cholate, Venenum Bufonis, Margarita, Borneolum Syntheticum, Radix Ginseng, Cornu Bubali dry extract are pulverized respectively, again with the Radix Notoginseng total arasaponins facing-up, sieve, mixing, with the general ball of ethanol, Radix Glycyrrhizae charcoal coating, cold drying makes pill;

    Described Radix Notoginseng total arasaponins is to get Radix Notoginseng powder to be broken into coarse powder, uses the 30-90% alcohol reflux, filter, filtrate decompression is concentrated into without the ethanol flavor, transfers PH to 6.0-6.5 with the 15%-30% hydrochloric acid solution, placement is spent the night, filter, filtrate is extracted with the ether jolting, discards ether solution, use water saturated n-butanol extraction, merge n-butyl alcohol liquid, the reclaim under reduced pressure n-butyl alcohol makes at 30-90 ℃

    of vacuum drying;

    Described Cornu Bubali dry extract is water intaking Cornu Bovis seu Bubali thin slice, adds 6-10 times of water gaging, decocts 1-3 time, and each 5-10 hour, collecting decoction filtered, and filtrate is condensed into thick paste, makes 80 ℃

    of lower dryings.

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