The purposes of pyrazolo [1,5-A] pyrimidine derivatives in the kinase whose medicine of preparation Profilin

The purposes of pyrazolo [1,5-A] pyrimidine derivatives in the kinase whose medicine of preparation Profilin

  • CN 101,360,499 B
  • Filed: 10/04/2006
  • Issued: 10/07/2015
  • Est. Priority Date: 10/06/2005
  • Status: Active Grant
First Claim
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1. treat at least one compound of effective dose or the purposes of the pharmaceutically acceptable salt of described compound in medicine preparation, described medicine is used for by suppressing CHK1 with disease therapy or the progress slowing down disease, and this compound is selected from:



  • 2. purposes according to claim 1, wherein said disease is cancer.3. purposes according to claim 1, wherein said medicine is the form giving following combination;

    (i) treats the compound of at least one claim 1 of effective dose or the pharmaceutically acceptable salt of described compound, with (ii) anticarcinogen.4. purposes according to claim 1, wherein said medicine is the form comprising following Pharmaceutical composition;

    the pharmaceutically acceptable carrier of (i) at least one, treats the compound of at least one claim 1 of effective dose or the pharmaceutically acceptable salt of described compound with (ii).5. purposes as claimed in one of claims 1-4, wherein the compound of claim 1 is;

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