Modified coagulation factor VIIa with extended half-life

Modified coagulation factor VIIa with extended half-life

  • CN 101,379,189 B
  • Filed: 02/03/2007
  • Issued: 09/03/2014
  • Est. Priority Date: 02/06/2006
  • Status: Active Grant
First Claim
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1. Albumin fusion polypeptide, it forms by merging to albuminous proconvertin or proconvertin a polypeptide, wherein said proconvertin or proconvertin a polypeptide are positioned at the N-end of described fusion polypeptide, and wherein said fusion polypeptide has the biologic activity of proconvertin/VIIa;

  • And wherein peptide linker separates the proconvertin of N-end or the proconvertin a part that are positioned at described fusion polypeptide with Albumin in Partial, described peptide linker by least 3 and at the most 31 amino acid form.

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