Formulations and methods for treating amyloidosis

Formulations and methods for treating amyloidosis

  • CN 101,528,216 A
  • Filed: 04/17/2006
  • Published: 09/09/2009
  • Est. Priority Date: 04/15/2005
  • Status: Active Application
First Claim
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1. the method for treatment or prevention target patient AA amyloidosis, described method comprises the following formula:

  • compound that gives described target patient treatment effective dose;

    Y-(CH 2) n-[CH 2Y] m??(I) When wherein Y occurs at every turn, independently be selected from SO 3X or OSO 3X;

    When X occurs at every turn, independently be selected from cation group;

    N is 1,2,3 or 4;

    M is 1 or 2, so that treatment or prevention AA amyloidosis make the parameter relevant with renal damage (PRI) keep acceptable toleration index (ATI) simultaneously, Wherein said target patient is just being accepted AA amyloidosis treatment, and has or to the parameter sensitivity relevant with renal damage.

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