Antimicrobial peptides

Antimicrobial peptides

  • CN 101,528,248 A
  • Filed: 07/10/2007
  • Published: 09/09/2009
  • Est. Priority Date: 07/10/2006
  • Status: Active Application
First Claim
Patent Images

1. having in antimicrobial acivity or the endotoxin and active peptide shown in the following formula:

  • (Xaa 1) M-(Xaa 2) O-Xaa 3-(Xaa 4) P-(Xaa 5) Q-(Xaa 6) M-(Xaa 7) R-(Xaa 8) S, wherein Xaa 1Be hydrophobic amino acid, be preferably selected from phenylalanine (Phe), alanine (Ala), leucine (Leu) and valine (Val), Xaa 2Be basic amino acid, be preferably selected from arginine (Arg) and lysine (Lys), Xaa 3Be hydrophobic amino acid, preferred color of choice propylhomoserin (Trp), Xaa 4Be selected from alanine (Ala), arginine (Arg), glutamine (Gln), agedoite (Asn), proline (Pro), isoleucine (Ile), leucine (Leu) and valine (Val), Xaa 5Be selected from isoleucine (Ile), phenylalanine (Phe), tryptophan (Trp) and tyrosine (Tyr), Xaa 6Be selected from arginine (Arg), lysine (Lys), tyrosine (Tyr) and phenylalanine (Phe), Xaa 7Be hydrophobic amino acid, be preferably selected from isoleucine (Ile), tryptophan (Trp), valine (Val) and leucine (Leu) and Xaa 8Be selected from arginine (Arg), lysine (Lys), isoleucine (Ile) and serine (Ser), and wherein O is 0,M is 1 or 2,P is 2 or 3,Q and R be 1 andS is 1,2,3 or 4.

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