Process for production of l-amino acid

Process for production of l-amino acid

  • CN 101,563,453 B
  • Filed: 09/06/2007
  • Issued: 05/28/2014
  • Est. Priority Date: 12/19/2006
  • Status: Active Grant
First Claim
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1. produce the amino acid whose method of L-for one kind, be included in substratum to cultivate and there is L-amino acids production ability and carried out modification and make the microorganism of succinic dehydrogenase activity and ketoglurate dehydrogenase activity decreased by the encode gene of succinodehydrogenase and the gene of the ketoglurate dehydrogenase of encoding of destructions, generate and accumulate thereby make L-amino acid in this substratum or in microbe, and from this substratum or microorganism-collecting L-amino acid, wherein said L-amino acid is Pidolidone, wherein said microorganism is Pantoea ananatisWherein said coding succinodehydrogenase gene is the one kind or two or more gene being selected from sdhA gene, sdhB gene, sdhC gene and sdhD gene, andThe gene of ketoglurate dehydrogenase of wherein encoding is sucA gene.

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