Combination of oral medication of glycyrrhizic acid or its salt and preparation method thereof

Combination of oral medication of glycyrrhizic acid or its salt and preparation method thereof

  • CN 101,600,439 A
  • Filed: 12/29/2007
  • Published: 12/09/2009
  • Est. Priority Date: 12/29/2006
  • Status: Active Application
First Claim
Patent Images

1. Claims1st, pharmaceutical composition, it is characterised in that:

  • Composition is composed of multiple units, and each unit includes content and wraps up the enteric coating of the content, and the weight ratio of content and enteric coating is 1;

    0.15-1 ;

    0.45, wherein the content contains glycyrrhizic acid or its salt and at least one intestinal absorption enhancers.2nd, the composition described in claim 1, wherein the weight ratio of the content and enteric coating is 1;

    0.2-1 ;

    0.4.3rd, the composition described in claim 2, wherein the weight ratio of the content and enteric coating is 1;

    0.25-1 ;

    0.35.4th, the composition described in claim 1-3, wherein the diameter of each unit is between 0.7mm ~ 1.2mm.5th, the composition described in claim 1-4, wherein the intestinal absorption enhancers are phospholipid substances.6th, the composition described in claim 1-5, wherein the content contains the phosphatide complexes formed by glycyrrhizic acid or its salt with phospholipid substance, and the weight ratio of glycyrrhizic acid or its salt and phospholipid substance is 1;

    0.5〜

    1 ·

    5.7th, the composition described in claim 1-5, wherein the glycyrrhizic acid or its salt are 18- α

    glycyrrhizic acids or its salt.8th, the composition described in claim 7, wherein the glycyrrhetate is the magnesium salts of 18- α

    glycyrrhizic acids and by salt.9th, the method for preparing the composition described in claim 1-8, it includes:

    Glycyrrhizic acid or its salt and intestinal absorption enhancers are mixed;

    And the mixture of gained is subjected to enteric coating.10th, the composition described in claim 1-8 prepare for treat hepatitis medicine in purposes.11. the composition described in claim 1-8 prepare for improve dysfunction of liver medicine in purposes.12. treating the method for the hepatitis of individual, including the individual is administered with any claim Suo Shu Group compounds in the claim 1-8 of therapeutically effective amount.13. improve individual dysfunction of liver method, including with any claim in the claim 1-8 of therapeutically effective amount composition the individual is administered.

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