Inhibitors of bruton's tyrosine kinase

Inhibitors of bruton's tyrosine kinase

  • CN 101,610,676 B
  • Filed: 12/28/2006
  • Issued: 03/27/2013
  • Est. Priority Date: 09/22/2006
  • Status: Active Grant
First Claim
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1. the compound of a following formula (D) or the acceptable salt of its medicine:

  • formula (D) Wherein;

    L ao;

    Ar is phenyl;

    Y is 4 yuan, 5 yuan, 6 yuan or 7 yuan of cycloalkyl rings;

    OrY is the heterocycloalkyl ring of 4 yuan, 5 yuan, 6 yuan or 7 yuan;

    Z is C (=O), NHC (=O) or S (=O) 2;

    R 7and R 8h, or R 7and R 8be combined together to form key;

    With R 6h.

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