Modified release solid or semi-solid dosage forms

Modified release solid or semi-solid dosage forms

  • CN 101,677,967 A
  • Filed: 06/09/2008
  • Published: 03/24/2010
  • Est. Priority Date: 06/12/2007
  • Status: Active Application
First Claim
Patent Images

1. solid or semi-solid medicament dosage form comprise:

  • A) first, it contains first active component that is made of NSAID and/or its officinal salt, wherein in described dosage form with after dissolution medium contacts, described first active component discharges from described dosage form in the mode that discharges at once basically;

    WithB) second portion, it containsI. particle cores, it is made of second active component;

    Ii. semipermeability coatings, it covers described particle cores basically to form coated granule;

    WithIii. protectiveness coatings, it covers described coated granule basically,Wherein in described dosage form with after described dissolution medium contacts, described second active component is released mode with accent and is discharged from described second portion,And wherein the curative effect lasting time of the curative effect lasting time of described second active component that discharges from the described second portion of described dosage form and described first active component is basic identical.

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