variant activin receptor polypeptides and uses thereof

variant activin receptor polypeptides and uses thereof

  • CN 101,679,980 A
  • Filed: 03/06/2008
  • Published: 03/24/2010
  • Est. Priority Date: 03/06/2007
  • Status: Active Application
First Claim
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1. the isolating protein that comprises variant activin IIB receptor polypeptides (vActRIIB), wherein said polypeptide comprises the peptide sequence of SEQ ID NO:

  • 2 or SEQ ID NO;

    18, but in the position 28 or 40 places, position have monamino acid to replace, and wherein said polypeptide can be in conjunction with flesh chalone, activator A or GDF-11.

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