Activin-ACTRII antagonist and the purposes in improving hematocrit level

Activin-ACTRII antagonist and the purposes in improving hematocrit level

  • CN 101,687,015 B
  • Filed: 12/18/2007
  • Issued: 08/03/2016
  • Est. Priority Date: 12/18/2006
  • Status: Active Grant
First Claim
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1. ActRII-Fc fusion protein is used for the purposes treated or prevent in the medicine of the anemia of human patients in preparation, and wherein said ActRII-Fc fusion protein is selected from following polypeptide:

  • A) polypeptide being made up of the aminoacid sequence of SEQIDNO;

    7,B) polypeptide being made up of the aminoacid sequence of SEQIDNO;

    20, andC) polypeptide being made up of the aminoacid sequence of SEQIDNO;

    21, andWherein said ActRII-Fc fusion protein combines activin or GDF11.

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