Determine the method for hepatocellular carcinoma hypotype and detection liver-cancer stem cell

Determine the method for hepatocellular carcinoma hypotype and detection liver-cancer stem cell

  • CN 101,711,287 B
  • Filed: 06/09/2008
  • Issued: 04/27/2016
  • Est. Priority Date: 06/08/2007
  • Status: Active Grant
First Claim
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1. biomarker specific oligonucleotide probe is preparing the purposes in medicament, and described medicament determines hepatocellular carcinoma (HCC) hypotype by following in curee:

  • A) liver cell sample is obtained from described curee,B) expression of one or more biomarkers of described sample is analyzed, andC) expression of one or more biomarkers described in described sample is associated with the hypotype of HCC in described curee,One or more biomarkers wherein said are selected from by miR-221] SEQIDNO;

    25] and the group that forms of the biomarker that identifies of miR-222 [SEQIDNO;

    26], andThe rise of one or more biomarkers described in wherein said sample is associated with (BDE) HCC hypotype of the epithelial duct in curee.

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