vaccine compositions containing amyloid beta1-6 antigen arrays

vaccine compositions containing amyloid beta1-6 antigen arrays

  • CN 101,711,865 A
  • Filed: 07/18/2003
  • Published: 05/26/2010
  • Est. Priority Date: 07/19/2002
  • Status: Active Application
First Claim
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1. compositions, it comprises:

  • (a) has the core granule of at least one first attachment site;

    With(b) at least one has the antigen or the antigenic determinant of at least one second attachment site,Wherein said antigen or antigenic determinant are A β

    1-6 peptides, and wherein said second attachment site is selected from;

    (i) non-natural is present in the attachment site on described antigen or the antigenic determinant;

    WithNaturally occurring attachment site on (ii) described antigen or the antigenic determinant,Wherein said second attachment site can associate with described first attachment site;

    And wherein said A β

    1-6 peptide and described core granule interact to form orderly and multiple antigen array by described association.

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