Monoclonal anti-beta amyloid antibody

Monoclonal anti-beta amyloid antibody

  • CN 101,802,007 B
  • Filed: 06/12/2008
  • Issued: 08/25/2017
  • Est. Priority Date: 06/12/2007
  • Status: Active Grant
First Claim
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1. antibody or its fragment, wherein the antibody or its fragments specific combination amyloid beta A β

  • 1-40, and comprising(i) light variable domains and (ii) heavy-chain variable domains, wherein light variable domains contain SEQ ID NO:

    7 aminoAcid sequence, heavy-chain variable domains contain SEQ ID NO:

    8 amino acid sequence,And wherein SEQ ID NO:

    The amino acid of 8 position 52 is cysteine,Wherein described fragment is the Fab of the antibody, F (ab '"'"') 2, scFv, or Fv fragments.

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